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As part of the Choosing Wisely campaign

AAP Outlines Appropriate Pediatric Nephrology Testing

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Five evidence-based recommendations list tests, procedures that doctors, patients should question
Cell-free DNA sequencing represents an advance in genomic medicine and has associated ethical challenges

Review Addresses Cell-Free DNA Sequencing in Pregnancy

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cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing
Treatment with lumpectomy and radiotherapy is associated with a reduction in breast cancer mortality versus lumpectomy or mastectomy alone among patients with ductal carcinoma in situ

Lumpectomy + Radiation May Cut Breast Cancer Mortality in DCIS

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Lumpectomy, radiotherapy tied to reduction in breast cancer mortality versus lumpectomy, mastectomy
A novel high-sensitivity cardiac troponin T protocol for ruling out myocardial infarction rules out more patients than the existing protocol

Novel hs-cTnT Protocol Better Rules Out Myocardial Infarction

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High-sensitivity troponin T rules out AMI in emergency department patients sooner than existing protocol
Many low-income urban preschool-aged children with asthma do not meet the criteria for home medication readiness

Many Children With Asthma Do Not Have Medications Ready

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Low-income urban preschoolers with asthma may not meet home medication readiness criteria
A brain stimulation device to treat obsessive-compulsive disorder has received approval for marketing by the U.S. Food and Drug Administration.

FDA Permits Marketing of Brain Stimulation Device for OCD

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FDA previously approved transcranial magnetic stimulation for major depression, certain migraines
A U.S. National Institutes of Health oversight panel will no longer review all applications for gene therapy experiments. Instead

Comments Open on End of NIH Review for Gene Therapy Studies

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NIH oversight panel no longer plans to review all applications for gene therapy experiments
A measles outbreak that's so far affected 21 states and the District of Columbia is being investigated by U.S. health officials.

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

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Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated
Systematic screening for anxiety

Psych Screening Beneficial in Pediatric Abdominal Pain

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Children with abdominal pain commonly had clinically significant anxiety, moderate disability, pain
Retrospective review of clinician documentation in the electronic health record can help identify diagnostic uncertainty with moderate reliability

EHR Review Can Measure Diagnostic Uncertainty

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For more than 70 percent of visits to a primary care clinic, reviewers identified diagnostic uncertainty