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Use of appropriate statistical methodology can allow for the synthesis of data collected as part of traditional clinical trials with real-world data

Tools, Methods of RCTs Can Be Adapted to Real-World Settings

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3 options described for applying approaches used in randomized controlled trials to real-world data
Most U.S. adults believe that marijuana has at least one benefit

Many U.S. Adults View Marijuana Use Positively

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81 percent believe marijuana has at least one benefit; 91 percent believe it has at least one risk
More than three-quarters of those living in residential care facilities have an advance directive

Majority of Those in Residential Care Have Advance Directives

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Geographical differences seen, with percentage of residents with directives ranging from 65% to 88%
Partners of people with newly diagnosed diabetes have small but significant differences in health-related behavioral changes compared with partners of people without diabetes

Diabetes Diagnosis May Impact Health Behaviors of Family

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Small changes in health behaviors seen for partners of those newly diagnosed with diabetes
Fertility rates among nearby populations appear to increase after coal and oil power plant retirements

Coal and Oil Power Plant Pollution May Lower Fertility Rates

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Findings based on pre-post study of coal and oil power plant retirements
There have been 11 lung-related infant deaths after pregnant women in the Netherlands were given sildenafil (Viagra) to boost the growth of their babies while in the womb.

11 Infant Deaths Halt Trial of Sildenafil in Pregnant Women

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Aim of the trial was to improve blood flow to the placenta and promote fetal growth
Cognitive function deficits resulting from indoor thermal conditions during heat waves affect university students

Reduced Cognitive Function for Students During Heat Waves

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Students with AC had increase in reaction time and reduction in throughput in two cognitive tests
Reducing the default number of opioid pills prescribed in an electronic medical record system can effectively decrease the amount of opioids prescribed after procedures

Lowering Default Number of Pills Can Reduce Prescribed Opioids

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Lowering the default number of pills prescribed in an EMR system effectively cuts amount prescribed
Parents' adverse childhood events

Parents’ Childhood Affects Their Children’s Behavioral Health

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Adverse childhood events for parents, especially mothers, affects kids' emotional well-being
Practices and physicians should prepare for emergency situations

Physicians and Practices Should Prepare for Emergencies

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Helpful strategies include developing a plan, knowing who will implement the plan, and staying flexible