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Individuals with Alzheimer's disease have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway

Abnormalities in Genes Linked to IRSP in Alzheimer’s Disease

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Abnormalities, reductions in gene expression associated with insulin receptor signaling pathway
Among patients in the intensive care unit

Notes Reflecting Financial Considerations ID’d in ICU

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Overall, 4.2 percent of admissions have at least one clinical note reflecting financial considerations
Public automated external defibrillators are cost-effective for out-of-hospital cardiac arrest and are associated with better outcomes

AHA: Public Automated External Defibrillators Are Cost-Effective

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Second study shows improved one-month survival with favorable neurological outcome with public AED use
Opioid use is associated with the risk for developing atrial fibrillation

AHA: Opioid Use Appears to Up Risk for Atrial Fibrillation

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Opioid prescription independently tied to likelihood of having atrial fibrillation in cohort of young veterans
The normal human appendix seems to contain pathogenic forms of α-synuclein

Removing Appendix May Lower Risk for Parkinson’s Disease

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Healthy human appendix contains intraneuronal α-synuclein aggregates, truncation products
Advanced paternal age is associated with adverse infant and maternal outcomes

Older Paternal Age Linked to Adverse Perinatal Outcomes

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Higher risk for premature birth, low birth weight, low Apgar score seen with older paternal age
Prenatal exposure to most medications affecting neurotransmitter systems is not associated with estimates of autism spectrum disorder risk

Most Meds Affecting Neurotransmitters Not Linked to Autism Risk

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Prenatal exposure to 5 groups of meds had nominally significant links to ASD
Pediatricians should educate parents about positive and effective discipline strategies for children and emphasize the importance of avoiding corporal punishment

AAP Warns of Harms of Corporal Punishment for Children

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Parents are encouraged to use healthy forms of discipline such as positive reinforcement
Existing tobacco control efforts will continue to reduce lung cancer mortality through 2065

Models Project 79 Percent Drop in Lung CA Mortality by 2065

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Annual number of deaths expected to continue to decrease despite growth, aging of U.S. population
Ruling against the recommendation of one of its chief experts

FDA Approves Powerful New Opioid Despite Criticisms

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Dsuvia use restricted to operating rooms or on the battlefield