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Piqray (alpelisib) tablets were approved for the treatment of hormone receptor-positive

First PI3K Inhibitor Approved for Metastatic, Advanced Breast Cancer

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Piqray approved for HR-positive, HER2-negative, PIK3CA-mutated, metastatic or advanced breast cancer
For patients with intracerebral hemorrhage

Antiplatelets Do Not Up Recurrence in Intracerebral Hemorrhage

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In population with cerebral microbleeds, no increased risk seen for those starting antiplatelet therapy
Suboptimal blood pressure and fasting glucose levels are associated with atrioventricular block

Suboptimal BP, Fasting Glucose Tied to Atrioventricular Block

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Two modifiable variables potentially explain more than half of all atrioventricular blocks
Many patients with noncurable pancreatic adenocarcinoma do not have a specialized cancer consultation and most do not receive cancer-directed therapy

Cancer Consultation Low in Noncurable Pancreatic Adenocarcinoma

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Likelihood of cancer-directed therapy higher for first consult with medical, radiation oncology versus surgery
In conjunction with the American Academy of Pediatric Dentistry

Guidance Updated for Sedation in Pediatric Dental Patients

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Importance of having two individuals present during deep sedation and/or general anesthesia emphasized
Deep learning models can improve the accuracy of lung cancer screening

AI Model Can Improve Accuracy of Lung Cancer Screening

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In some situations, model outperformed radiologists with reductions in false positives, negatives
Regulation of the intestinal microbiota appears to be effective for improving anxiety symptoms

Regulation of Intestinal Microbiota Beneficial for Anxiety

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Six of seven studies using nonprobiotics as interventions were effective
Increased body mass index in adolescence is associated with an increased risk for cardiomyopathy in adulthood among men

Higher BMI in Male Teens Tied to Cardiomyopathy in Adulthood

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Risk increased even at BMI considered normal; more than eightfold greater risk seen for BMI ≥35 kg/m²
Lower socioeconomic status is associated with an increased risk for above-knee amputation after periprosthetic joint infection of the knee

Poverty Ups Risk for Amputation After Knee Replacement

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No racial or sex disparities seen for risk for amputation after periprosthetic joint infections

American Psychiatric Association, May 18-22

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The 172nd American Psychiatric Association Annual Meeting The annual meeting of the American Psychiatric Association was held from May 18 to 22 in...