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Heart disease is associated with an increased risk for hospital admission for allopurinol-associated severe cutaneous adverse reactions

Heart Disease May Up Risk for Allopurinol-Linked Cutaneous AEs

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Risk for hospital admission increased for allopurinol-associated severe cutaneous adverse reactions
Multiple mental illnesses are associated with an increased risk for cardiovascular disease outcomes in veterans

Most Severe Forms of Mental Illness Lead to Highest CVD Risk

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Findings seen in both male and female veterans with psychotic disorders such as schizophrenia
Women undergoing vaginal birth after cesarean are more likely to have adverse maternal birth-related complications and perinatal outcomes

Adverse Outcomes Up for Vaginal Birth After Previous C-Section

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However, women with planned VBAC more likely to breastfeed at birth, discharge, and six to eight weeks
Childhood secondhand smoke exposure predicts an increased risk for adulthood atrial fibrillation after adjusting for other risk factors

Childhood Secondhand Smoke Tied to Later Atrial Fibrillation

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Each pack/day increase in parental smoking ups offspring risk by 18 percent
Delay in referral for colorectal cancer in primary care is associated with low cancer suspicion

Low Cancer Suspicion Tied to Delay in CRC Referral in Primary Care

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Presentation without alarm symptoms linked to long duration to referral in multivariable analysis
More patients with advanced melanoma receiving nivolumab plus ipilimumab or nivolumab alone have sustained long-term survival at five years compared with those receiving ipilimumab alone

Nivolumab Therapy Prolongs Survival in Advanced Melanoma

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Overall survival at five years longer with nivolumab + ipilimumab, nivolumab alone versus ipilimumab
For patients with progressive fibrosing interstitial lung diseases

Nintedanib Slows Fibrosing Interstitial Lung Disease

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Nintedanib linked to lower rate of decline in forced vital capacity versus placebo in phase 3 trial
Sports specialization is associated with a greater volume of vigorous sports activity and increased risk of injury

Sports Specialization Ups Injury Risk, Especially in Girls

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Volume of vigorous activity is a strong predictor of injuries for both boys and girls
Between 2009 and 2017

2009 to 2017 Saw Pediatric Developmental Disability Increase

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Significant increases in prevalence of any developmental disability and in ADHD, ASD, intellectual disability
Eight candidate touchpoints are associated with increased risk of fatal opioid overdose

Eight Touchpoints May Predict Opioid Overdoses

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These factors identify more than half of opioid overdose decedents and may represent prevention opportunities