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Monthly Archives: June 2020

For women with premature ovarian insufficiency

Contraceptives Beneficial for Premature Ovarian Insufficiency

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Combined oral contraceptives linked to improvement in bone mass, similar to that with high-dose HT
Allopurinol does not affect estimated glomerular filtration rate in patients with chronic kidney disease and does not result in a clinically meaningful benefit in kidney outcomes from serum urate reduction among patients with type 1 diabetes and early-to-moderate diabetic kidney disease

Allopurinol Does Not Affect eGFR in Chronic Kidney Disease

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And, serum urate lowering with allopurinol did not affect GFR in T1DM and diabetic kidney disease
Most of the decline in infant mortality rates from 2000 to 2017 was due to declines in rates across maternal age groups

Drop in Infant Mortality Mainly Due to Drop Across Maternal Age

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Changes in age distribution of women giving birth accounted for part of drop in infant mortality rates
Sex and ethnicity differential patterns of COVID-19 positivity are not explained by cardiometabolic

Sex, Ethnic Differential Patterns of COVID-19 Unexplained

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Increase in COVID-19 for men, BAME not due to cardiometabolic, sociodemographic, behavioral factors
Inhibition of sclerostin with romosozumab may increase cardiovascular risk

Inhibition of Sclerostin May Increase Cardiovascular Risk

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SOST genetic variants linked to lower risk for fracture and osteoporosis but higher risk for MI, major CV AEs
It is possible to predict the likelihood of testing positive for COVID-19

Model May Help Predict Risk for Testing Positive for COVID-19

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Risk reduced with pneumococcal polysaccharide, flu vaccine; melatonin, paroxetine, or carvedilol use
The prevalence of metabolic syndrome among young adults in the United States is rising

Metabolic Syndrome Up in Young Adults in the United States

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Significant increases between 2011 and 2016 also seen for women, Asians, and Hispanics
Triple therapy

Triple Inhaled Therapy Aids in Moderate-to-Very Severe COPD

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Benefit seen for twice-daily triple inhaled therapy with glucocorticoid, glycopyrrolate, formoterol
Factors readily available in administrative data can predict five- and 10-year mortality in older adults with diabetes

Administrative Data Predict Mortality With Diabetes

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Thirty-seven factors have good accuracy for predicting five- and 10-year mortality in older veterans
The U.S. burden of skin and subcutaneous diseases is large but varies geographically

U.S. Burden of Skin and Subcutaneous Diseases Increasing

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Increases seen across all 50 states, with geographic variation in percentage