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Monthly Archives: March 2020

Insulin and other biologic drugs

FDA: Insulin Among Drugs Transitioned to Biological Products

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New regulatory pathway for biologic drugs allows for approval of biosimilars, interchangeable versions
Strong demand for medications that show promise as treatments for COVID-19 have led to shortages of those drugs in the United States.

Shortages Seen for Drugs That Show Promise Against COVID-19

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Patients who currently rely on remdesivir or hydroxychloroquine now facing dangerous shortages
In an American Academy of Pediatrics policy statement

Recommendations Issued for Pediatric Abuse-Related Head Trauma

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Recommendations for pediatricians include remaining vigilant for signs, consulting subspecialists
Sleep-disordered breathing is associated with changes in the brain

Sleep-Disordered Breathing Tied to Brain Changes

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Greater amyloid burden seen in regions of the brain tied to Alzheimer disease
Higher intake of foods like tofu with isoflavones is associated with a moderately lower risk for developing coronary heart disease

Plant-Based Proteins Can Help Cut Risk for Coronary Heart Disease

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Association strongest among premenopausal women, postmenopausal women without hormone use
There is currently no evidence that SARS-CoV-2 undergoes intrauterine or transplacental transmission from coronavirus disease 2019-infected pregnant women to fetuses

No Evidence Found for SARS-CoV-2 Vertical Transmission to Fetus

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No maternal-fetal transmission of SARS-CoV-2 seen to date in pregnant women with COVID-19
In a special article published online March 17 in Clinical Gastroenterology and Hepatology

Information on COVID-19 Provided for Gastroenterologists

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COVID-19 can include GI symptoms such as diarrhea; gastrointestinal tract is potential route of infection
In a letter to the editor published online Feb. 25 in Surgical Infections

Anesthesia Procedure Outlined for Emergency Surgery in COVID-19 Patients

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Fast induction of anesthesia with adequate muscle relaxation recommended to prevent cough
For men

Early Age at Puberty Linked to Increased T2DM Risk in Men

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Early age at peak height velocity also an independent predictor for insulin treatment for T2DM
Inhibition of interleukin-1β with canakinumab is associated with reduced incident anemia as well as improved hemoglobin levels among patients with baseline anemia

Interleukin-1β Inhibition Linked to Reduced Incidence of Anemia

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Among those with baseline anemia, hemoglobin levels improved with canakinumab versus placebo