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Monthly Archives: April 2019

For patients with FMS-like tyrosine kinase 3 mutations who have relapsed or refractory acute myeloid leukemia

AACR: Longer Survival With Gilteritinib in FLT3mut+ AML

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Longer overall survival, better remission rates seen for patients receiving gilteritinib versus salvage chemo
Liquid meal replacements in weight loss diets lead to modest reductions in cardiometabolic risk factors for overweight and obese patients with type 2 diabetes

Liquid Meal Replacements Cut Cardiometabolic Risk Factors

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Effects observed in overweight/obese patients with T2DM; certainty of evidence low to moderate
Higher body mass index

AACR: High BMI Before 50 Raising Pancreatic Cancer Mortality

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Twenty-eight percent of pancreatic cancer deaths due to higher BMI in those born in 1970 to 1974
Higher consumption of certain vitamins and carotenoids is associated with a significantly decreased risk for age-related cataract in cohort studies

Vitamins, Carotenoids Associated With Lower Risk for Cataract

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However, strongest evidence comes from cohort studies, not randomized controlled trials
The rates of compression-only cardiopulmonary resuscitation (CPR) and standard CPR arrival of emergency medical services increased and are associated with improved survival over no CPR

Rates of CPR Before EMS Arrival Increased From 2000 to 2017

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Compression-only, standard CPR have increased, linked to doubled survival rates versus no CPR
The 2009 changes to the U.S. Special Supplemental Nutrition Program for Women

Changes to WIC Food Program Tied to Reversal in Obesity Trends

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Trend of increasing obesity among 2- to 4-year-olds was reversed after 2009 changes
Shift work is associated with an increased risk for ischemic heart disease

Meta-Analysis Links Shift Work to Risk for Ischemic Heart Disease

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Positive dose-response relationship ID'd between risk for IHD, increasing duration of shift work
Women at risk for gestational diabetes mellitus who are not screened or diagnosed are more likely to experience stillbirth than women who undergo screening

Undiagnosed Gestational Diabetes Ups Risk for Stillbirth

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Women at risk for GDM who are screened, those diagnosed with GDM not at increased risk
The forms of medical cannabis used vary for patients with and without cancer

Cannabis Products Used Differ for Cancer, Noncancer Patients

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Cancer patients more likely to use sublingual tincture form; noncancer patients often use vaporization form
For patients with severe hemoglobinopathies undergoing bone marrow transplantation

Increasing Dose for Total Body Irradiation Cuts Graft Failure

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Findings seen in patients with severe hemoglobinopathies receiving haploidentical bone marrow transplantation