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Monthly Archives: April 2019

U.S. Food and Drug Administration approval of Ibrance (palbociclib) capsules has been widened to include men with hormone receptor-positive

Ibrance Approval Expanded to Include Men With Breast Cancer

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Kinase inhibitor approved in combination with endocrine therapy for male patients with breast cancer
For women with cervical intraepithelial neoplasia grade 2 or 3 associated with high-risk human papillomavirus

Histologic Clearance of CIN2/3 Seen With HPV Therapeutic Vaccine

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In phase II trial, rate of complete resolution of CIN2/3 significantly higher for vaccine versus placebo group
The prevalence of chronic obstructive pulmonary disease among individuals who have never smoked is high in certain industries and occupations

CDC: Prevalence of COPD High Among Some Nonsmokers

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High prevalence observed in certain industries and occupations, including information industry
There is a positive association between use of topical corticosteroids and incident type 2 diabetes

Topical Corticosteroids Associated With Higher Risk for Type 2 Diabetes

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Dose-response relationship observed in large European cohort
Among U.S. veterans with HIV infection

Depressive Symptoms May Up Risk for Death in HIV+ Veterans

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However, depression linked to higher risk for death in HIV-uninfected, but not HIV-infected, U.S. veterans
Several patient behaviors are associated with weight regain after Roux-en-Y gastric bypass surgery

Patient Behaviors Identified That Impact Weight Regain After RYGB

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Independent links for sedentary time, eating fast food, eating when feeling full, eating continuously
There is no clinically meaningful long-term association between pregnancy history and age-related change in cognitive function

Pregnancy History Not Likely Tied to Later Cognitive Function

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Authors say childbearing decisions and timing have no long-term impact on cognitive function
In older women

Digital Breast Tomosynthesis Boosts Metrics in Older Women

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DBT yielded lower abnormal interpretation rate, higher positive predictive value 1, higher specificity
In patients with myalgic encephalomyelitis/chronic fatigue syndrome

No Benefit Seen With Rituximab for Chronic Fatigue Syndrome

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B-cell depletion using several rituximab infusions over 12 months not linked to clinical improvement
Higher levels of dietary and supplementary calcium intake appear to be associated with a lower incidence of progression to late age-related macular degeneration

Calcium Intake Tied to Lower Rate of Late AMD

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Patients encouraged to continue taking calcium if needed for other indications