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Yearly Archives: 2018

Provider collaboration with local specialty pharmacies is associated with reduced delays in therapy and lower rates of direct-acting antiviral denial for patients with hepatitis C

Pharmacies Can Up Access to Direct-Acting Antivirals for Hep C

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Collaboration with local specialty pharmacy linked to reduced delays in therapy, lower rates of denial
The risk of autism spectrum disorder is reduced in offspring with maternal exposure to folic acid and multivitamin supplementation before and during pregnancy

Maternal Folic Acid, Multivitamin Use May Cut ASD Risk in Offspring

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Autism spectrum disorder risk lower in those whose moms took supplements before, while pregnant
TP53 pathogenic variants are overrepresented in children with acute lymphoblastic leukemia and are associated with worse outcomes

TP53 Variants Linked to Childhood ALL, Poor Outcomes

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Carrying germline variants linked to decreased event-free, overall survival; higher risk of second cancers
Type 1 interferons may mediate pregnancy complications in the context of congenital Zika virus infection

Type 1 IFNs May Mediate Zika Pregnancy Complications

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After Zika virus infection, IFNAR signaling in conceptus inhibits development of placental labyrinth
The Pain Self-Efficacy Questionnaire successfully demonstrates the extent of debility in migraine surgery patients and puts migraine pain in perspective within the realm of other known pain conditions

Pain Self-Efficacy Questionnaire Helps to Evaluate Migraine Pain

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Commonly used pain survey better assesses migraine patients' pain-coping ability and function
The new adjuvanted herpes zoster subunit vaccine is cost-effective compared with the currently recommended live attenuated herpes zoster vaccine

Adjuvanted Shingles Subunit Vaccine Likely More Cost-Effective

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Less overall cost and more effective than live attenuated vaccine at all ages; generally a good value
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

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Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans
For patients with type 1 diabetes

Bidirectional Association for Depression, Dysglycemia in T1DM

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Depression increases risk of dysglycemia especially in first six months to one year of diagnosis
Many patients with arteriovenous malformations of the brain have somatic activating KRAS mutations

KRAS Mutations Linked to Brain Arteriovenous Malformations

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Most tissue samples of arteriovenous malformations of the brain had somatic activating KRAS mutations
In both men and women in the United States

Cancer Death Rate Continuing to Decline in United States

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Continuous drop in combined cancer death rate from 1991 to 2015, resulting in 2,378,600 fewer deaths