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Yearly Archives: 2018

Sustained and increasing BACE1 inhibition can reverse amyloid deposition in a mouse model of Alzheimer's disease

In Alzheimer’s, BACE1 Inhibition May Reverse Amyloid Deposition

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Sequential, increased deletion of BACE1 in adult AD mouse model reversed amyloid deposition
For low risk patients with suspected pulmonary embolism

Safety of PERC Tool Validated for Very Low Risk PE Rule Out in ER

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Eight-item, pulmonary embolism rule-out criteria safe for use with very low risk patients in ER
Genetic stratification should play a role in the clinical care of patients with noncompaction cardiomyopathy

Genetics Should Inform Care in Noncompaction Cardiomyopathy

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Genetic status linked to risk of major adverse cardiac events in NCCM patients
Children with autism spectrum disorder have a significantly greater mean depth of ultrasonographic penetration

Mean Depth of Ultrasonographic Penetration Greater in Autism

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Greater depth in first trimester versus developmental delay group, typical development group
For obese adults with type 2 diabetes

Greater Weight Loss With RYGB in Obese With T2DM at Three Years

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Lasting improvements in weight, HbA1c, cardiovascular risk vs. intensive weight management
During 2013 to 2016

During 2013 to 2016, 8.1 Percent of U.S. Adults Had Depression

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Depression more common in women; lower among non-Hispanic Asians than other ethnic groups
The Affordable Care Act dependent coverage provision is associated with increased early and adequate prenatal care and decreased preterm births

ACA Dependent Coverage Tied to Increased Prenatal Care

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Increased early, adequate prenatal care, decreased preterm birth, especially among unmarried women
Higher concentrations of perfluoroalkyl substances are associated with greater weight regain in a diet-induced weight-loss setting

Perfluoroalkyl Substances Linked to Greater Weight Regain

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Higher baseline levels of PFAS tied to greater weight regain in weight-loss setting, especially for women
Four best practices outlined that can help prevent health care cyberattacks

Four Best Practices Outlined to Prevent Health Care Cyberattacks

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Health care execs should ID potential inefficiencies in cybersecurity, ensure systems backed up
Lipoproteins and lipids are similarly associated with risk of myocardial infarction and ischemic stroke but not intracerebral hemorrhage

Lipoproteins, Lipids Have Similar Ties to MI, Ischemic Stroke

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No association with ICH; within HDL, cholesterol inversely and triglyceride positively linked to MI