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Monthly Archives: September 2018

Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage

Drug Prices Increase More Than Expected After Shortages

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Expected price increase 20 percent for all drugs after shortage versus 9 percent in absence of shortage
Half of trials on the European Union Clinical Trials Register are non-compliant with the European Commission's requirement that all trials post results to the registry within 12 month of completion

Compliance With Requirement to Report Results on EUCTR Is Poor

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Half of trials on European Union Clinical Trials Register are non-compliant with requirements
From 2006 to 2015

2006 to 2015 Saw Increase in Severe Maternal Morbidity

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Forty-five percent increase in rate of severe maternal morbidity at delivery; higher rate for black women
For high-risk patients with implantable cardioverter-defibrillators (ICDs)

Ranolazine Doesn’t Cut VT, VF, Death in High-Risk ICD Patients

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No significant reduction in VT or VF or death risk for patients with implantable cardioverter-defibrillators
Clinicians advising families living overseas in highly polluted settings should understand their patients' concerns and have a network of resources to draw upon for guidance

Tips for Advising Patients Living in Highly Polluted Settings

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Guidance focuses on Americans posted in overseas settings with high ambient levels of air pollution
A new report finds that foster children are often given powerful psychiatric medicines without regard for proper safeguards.

Many Foster Kids Inappropriately Prescribed Psychiatric Drugs

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Some children may be getting meds they don't need, others may be going without drugs that may help
The PK Papyrus Covered Coronary Stent System has been approved by the U.S. Food and Drug Administration to treat acute coronary artery perforations.

FDA Approves Device for Acute Coronary Artery Perforations

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The PK Papyrus device is a balloon-expandable covered coronary stent and delivery system
Following implementation of a federal mandatory safety standard on infant walkers in 2010

Decrease in Infant Walker-Related Injuries Since 2010

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Decrease in injuries following implementation of federal mandatory safety standard in 2010
Over the last two decades

Proportion of Female Authors Rising in Cardiology Literature

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Over last two decades, increases in proportion of women as first authors, senior authors
Variables have been identified that predict escalated care for infants with bronchiolitis

Factors Predictive of Escalated Care in Infant Bronchiolitis ID’d

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Include oxygen saturation < 90 percent, nasal flaring/grunting, apnea, retractions, age ≤2 months