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Monthly Archives: August 2018

Retrospective review of clinician documentation in the electronic health record can help identify diagnostic uncertainty with moderate reliability

EHR Review Can Measure Diagnostic Uncertainty

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For more than 70 percent of visits to a primary care clinic, reviewers identified diagnostic uncertainty
The first generic version of the EpiPen has been approved by the U.S. Food and Drug Administration

FDA Approves First Generic EpiPen

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Approval will address both rising costs and shortages of epinephrine
Six cases of corneal infections associated with sleeping in contact lenses are described in a case report published in the Aug. 17 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Report Details Corneal Infection Tied to Sleeping in Contacts

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Six patients reported sleeping in lenses on regular basis; most had vision loss, permanent damage
Ingesting honey after swallowing a button battery may reduce injuries and improve outcomes in children

Honey May Protect Children Who Swallow Button Batteries

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Honey and Carafate appear to rapidly protect against batteries' caustic effects
Administering the Visual Association Test improves the predictive value of the Mini-Mental State Examination score for dementia

VAT Score Improves Predictive Value of MMSE for Dementia

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Imperfect VAT score plus decline in MMSE score over two years helps identify those at higher risk
Electronic cigarette (e-cigarette) vapor condensate is significantly more toxic to alveolar macrophages than e-cigarette liquid

E-Cigarette Vapor Condensate Toxic to Alveolar Macrophages

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Vapor condensate cytotoxic at lower concentrations than e-cigarette liquid, results in increased apoptosis
Pediatric patients with chronic kidney disease have higher global cerebral blood flow and regional differences in cerebral blood flow

Cerebral Blood Flow Changes in Pediatric Patients With CKD

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Pediatric patients with CKD showed higher global CBF attributed to reduced hematocrit level
Significant improvements in neonatal abstinence syndrome outcomes can result from a comprehensive quality improvement program

QI Program Can Up Outcomes for Neonatal Abstinence Syndrome

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Decreases in pharmacologic treatment, adjunctive agent use, hospital length of stay, opioid tx days
Little excess risk of death is seen for patients with type 2 diabetes with five risk-factor variables within target ranges

Risk of Death Not Up in T2DM When Risk Factors Within Target

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Little or no excess risk of death, MI, stroke for those with five risk-factor variables within target ranges
From 2014 to 2017 there was an increase in tianeptine exposure calls reported by poison control centers to the National Poison Data System

CDC: Increase in Tianeptine Exposures From 2014 to 2017

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Most commonly reported health effects were neurologic, cardiovascular, and gastrointestinal