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Monthly Archives: June 2018

The first biosimilar drug to Neulasta has been approved by the U.S. Food and Drug Administration. Fulphila (pegfilgrastim) is approved for patients with non-myeloid cancer who are receiving myelosuppressive chemotherapy and have symptoms of febrile neutropenia.

FDA OKs 1st Biosimilar to Prevent Chemo-Related Infections

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Fulphila, biosimilar to Neulasta, helps reduce risk of infection during cancer treatment
Screening adults

USPSTF Advises PCPs to Screen Adults for Unhealthy Alcohol Use

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Screening, counseling advised for adults, including pregnant women; evidence lacking for teens
There is considerable variation in office-based physician visit rates by patient age and sex

CDC: Office-Based Physician Visit Rates Vary by Patient Age, Sex

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Visit rates for females exceeded that for males; rates for infants, seniors exceeded that for those age 1-64
Different target ranges for oxygen saturation as measured by pulse oximetry do not affect the composite primary outcome of death or major disability for extremely preterm infants

Similar Primary Outcome for Lower O2 Sat in Extreme Preterm

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No significant difference in composite outcome of death, major disability for extremely preterm infants
A noninvasive method for diagnosing irritable bowel syndrome

DDW: Bowel Sounds May Identify Irritable Bowel Syndrome

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Recording of bowel sounds allowed for IBS diagnosis with high sensitivity and specificity
In the field of fecal microbiota transplantation

DDW: Altruism, Economic Reward Motivate Fecal Donation

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Logistics of collecting and transporting feces was recurrent theme impeding stool donation
The addition of ovarian suppression to tamoxifen is associated with increased survival versus tamoxifen alone among premenopausal women with breast cancer

ASCO: Ovarian Suppression + Tamoxifen Ups Breast CA Survival

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Increased disease-free, overall survival for premenopausal women with breast cancer
Limited health literacy is a barrier to cardiovascular health and prevention of cardiovascular disease

AHA: Limited Health Literacy Is Barrier to Cardiovascular Care

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Use of Universal Precautions Toolkit recommended for improving quality of care
Direct supervision in which attending physicians join work rounds does not reduce the rate of medical errors

Direct Supervision by Attendings Doesn’t Reduce Medical Errors

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Direct supervision in which attending physicians join work rounds does not affect medical error rate
Youth with asthma have considerably higher use of tobacco products than those without asthma

Greater Use of Tobacco Products Among Youth With Asthma

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E-cigarettes most commonly used product among middle-, high-school students with, without asthma