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Monthly Archives: February 2018

The therapeutic significance of losartan in Marfan syndrome may lie in its ability to activate protective endothelial function

Losartan May Improve Endothelial Function in Marfan Syndrome

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Therapeutic importance may be increased in endothelial nitric oxide release, not ATR1 inhibition
Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain

Treating Depression Found to Up Successful Opioid Cessation

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Taking antidepressants helped non-cancer pain patients successfully stop long-term opioid use
Racial and ethnic disparities in the use of preoperative chemotherapy exist among patients with gastric cancer in the United States

Disparities Seen in Gastric Cancer Patients’ Receipt of Pre-Op Chemo

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Racial, ethnic disparities in treatment also affect disparities in overall survival
The Braden QD Scale reliably predicts both immobility-related and device-related pressure injuries in hospitalized pediatric patients

Risk Tool Predicts Pressure Injuries in Hospitalized Children

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Braden QD Scale reliably predicts pressure injuries related to immobility, medical devices
Omalizumab

Omalizumab Effective for Chronic Spontaneous Urticaria

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In small study, 85 percent of refractory CSU patients had complete response; rest had well-controlled dx
Excess weight loss immediately preceding bariatric surgery is associated with improved outcomes

Pre-Op Weight Loss Improves Outcomes of Bariatric Surgery

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Pre-op excess weight loss tied to significantly greater rate of post-op excess weight loss over one year
Evidence for the effectiveness of cranial electrical stimulation is sparse

Limited Evidence for Effect of Cranial Electrical Stimulation

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No significant benefit for patients with fibromyalgia, pain; conflicting results for painful conditions
Opioid use is associated with elevated risk of invasive pneumococcal disease

Opioid Use Linked to Risk of Invasive Pneumococcal Disease

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Strongest associations seen for opioids that were long acting, of high potency, and used at high doses
The risk of fatal traffic crashes is increased on April 20 in the United States

Risk of Fatal Traffic Crashes Up After April 20 Cannabis Event

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Increased risk of fatal crashes on cannabis celebration day in the U.S., especially among younger drivers
Electronic health records are not sufficient to ensure success in value-based care

EHRs Not Sufficient to Ensure Success in Value-Based Care

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EHRs do not necessarily capture information needed; interoperability is poor, analytics are incomplete