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Monthly Archives: February 2018

Nusinersen is associated with significant and clinically meaningful improvement in motor function among children with later-onset spinal muscular atrophy

Nusinersen Beneficial in Later-Onset Spinal Muscular Atrophy

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Significant improvement in motor function compared with sham procedure among children with SMA
A model with four categories has been developed to stratify patients with symptomatic long bone metastases based on their expected survival

New Model Stratifies Patients With Long Bone Metastases

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Model includes four prognostic categories with clinical consequences to predict median survival
From 1984 to 2012

Kidney Stone Incidence Increased Between 1984 and 2012

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The increase included both symptomatic and asymptomatic kidney stones
The burden of surgical site infection after gastrointestinal surgery is greater for countries with low income as classified by the U.N. Human Development Index

GI Surgical Site Infections Higher in Low-Income Countries

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Infection risk highest in countries with low income, low Human Development Index
Very low-dose 222-nm UVC ultraviolet light can inactivate more than 95 percent of aerosolized H1N1 influenza virus

Low Dose-Rate Far-UVC Light Can Inactivate Influenza Virus

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Far-UVC at 222-nm light can inactivate aerosolized viruses; >95 percent of H1N1 influenza inactivated
Women undergoing screening breast magnetic resonance imaging have higher biopsy rates and significantly lower cancer yield findings compared with screening mammography alone

Higher Biopsy Rates for Women Undergoing Screening Breast MRI

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Lower cancer yield compared to mammography alone for women with, without personal history of cancer
Sustained and increasing BACE1 inhibition can reverse amyloid deposition in a mouse model of Alzheimer's disease

In Alzheimer’s, BACE1 Inhibition May Reverse Amyloid Deposition

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Sequential, increased deletion of BACE1 in adult AD mouse model reversed amyloid deposition
For low risk patients with suspected pulmonary embolism

Safety of PERC Tool Validated for Very Low Risk PE Rule Out in ER

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Eight-item, pulmonary embolism rule-out criteria safe for use with very low risk patients in ER
Genetic stratification should play a role in the clinical care of patients with noncompaction cardiomyopathy

Genetics Should Inform Care in Noncompaction Cardiomyopathy

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Genetic status linked to risk of major adverse cardiac events in NCCM patients
Children with autism spectrum disorder have a significantly greater mean depth of ultrasonographic penetration

Mean Depth of Ultrasonographic Penetration Greater in Autism

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Greater depth in first trimester versus developmental delay group, typical development group