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Yearly Archives: 2017
PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors
Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations
Connective Tissue Disease May Raise Post-Abdominoplasty Risks
Higher risk of venous thromboembolism, need for blood transfusion for patients with CTD
Midlife Systemic Inflammation Tied to Late-Life Brain Volume
Smaller hippocampal, Alzheimer's signature region volumes seen 24 years after inflammation noted
Gene Replacement Tx Beneficial in Spinal Muscular Atrophy
And nusinersen improves motor-milestone response for infants with spinal muscular atrophy
ACE Inhibitor, Statin No Benefit for T1DM, High Albumin Excretion
Use of ACE inhibitor and a statin does not change albumin-to-creatinine ratio in adolescents with T1DM
Nutritional Therapy Beneficial in Chronic Kidney Disease
Management of uremia, electrolyte imbalances, water/salt retention may help increase longevity
Liposuction Can Reduce Lymphedema-Related Swelling
Case report describes beneficial effect for three patients with lymphedema affecting the leg or arm
Driving Impairment Warnings Often Not Given With Rx Meds
For most drug categories, those who do receive warnings perceive higher risk of impaired driving
GLP-1 May Mediate Effects of Gastric Bypass on CNS Activation
After Roux-en-Y, CNS activation reduced in response to food cues, GLP-1 levels significantly elevated
PPI-Gastric Cancer Link Remains After H. Pylori Eradication
Increased risk seen in H. pylori-infected subjects who received eradication therapy
