Hospital Discharges for Prescription Opioids Have Fallen
But inpatient and ED discharges related to heroin have increased in past decade
Adding Surveillance to FIT Screening Cuts CRC Mortality
But addition of surveillance is not cost-effective based on Dutch incremental cost-effectiveness ratio
Opioid Manufacturers to Provide Doctor Training
74 manufacturers of immediate-release opioids notified that drugs will be subject to requirements
Recent Immigrants to Canada More Likely to Die in ICU
Immigrants more likely than long-standing residents to receive aggressive care in six months before death
Low-Dose Alteplase No Better for Acute Ischemic Stroke
No differences between low, standard dose in treatment effects for poor outcomes by age, ethnicity
Vancomycin + Piperacillin/ Tazobactam Ups Kidney Risk
Risk of AKI in hospitalized children higher than with IV vancomycin, other antipseudomonal β-lactam
Skipping Breakfast Tied to Increased Odds of Atherosclerosis
Odds of noncoronary, generalized atherosclerosis up independent of traditional, dietary CV risk factors
Tdap Given in Pregnancy Protects Infants From Pertussis
Multivariable vaccine effectiveness estimate 77.7 percent for Tdap administered during third trimester
Liraglutide Tied to Significant Weight Loss in Obese
The drug slows gastric emptying of solids, which may be a biomarker of responsiveness
Hypermutated ctDNA Linked to Checkpoint Inhibitor Response
Patients with high alteration number in variants of unknown significance had better outcomes
