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Monthly Archives: October 2017

Extended-release naltrexone is noninferior to buprenorphine-naloxone for maintaining short-term abstinence from heroin and other illicit substances

Extended-Release Naltrexone Promising for Opioid Dependence

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Lower use of heroin, other illicit opioids with extended-release naltrexone in superiority analysis
Identification of mitral regurgitation should prompt evaluation of its etiology

New Expert Consensus Pathway for Mitral Regurgitation

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Etiology, mechanism, severity, indications for treatment should be assessed after MR is identified
Many authors of dermatology clinical practice guidelines receive industry payments

Many Dermatology Guideline Authors Get Industry Payments

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22 of 40 guideline authors receiving payments did not accurately disclose industry relationships
For patients undergoing left colon and rectal cancer resections

Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection

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Adding antibiotics to mechanical bowel preparation linked to reduced rate of surgical site infection
Sharing of passwords to access electronic medical records is common among medical staff members

Sharing Passwords Is Widespread Among Medical Staff

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Almost three-fourths of survey respondents report having used a colleague's password to access EMRs
Adding a sulfonylurea or metformin to insulin is associated with approximately a 1 percent reduction in hemoglobin A1c

Clinical Evidence Synopsis Published for T2DM

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Adding sulfonylurea or metformin to insulin decreases HbA1c about 1%
For individuals with impaired glucose regulation

Lifestyle, Metformin Interventions Have Variable Effects

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Impact of interventions varies for progression to diabetes, regression to normal glucose regulation
Proton pump inhibitor use is associated with increased risk of first-time ischemic stroke and myocardial infarction

PPI Use Linked to Increased Risk of Ischemic Stroke, MI

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Risks of first-time stroke, myocardial infarction up especially for long-term users, at high doses
Introduction of an HIV pre-exposure prophylaxis program for men who have sex with men in the United Kingdom is likely to be cost-effective

Pre-Exposure Prophylaxis for Homosexual Men Cost-Effective

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Introduction of HIV PrEP program cost-effective and possibly cost-saving for men who have sex with men
For patients with venous thromboembolism

No Increased Risks for DOAC Use Versus Warfarin in VTE

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Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism