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Monthly Archives: September 2017

For university students with insomnia

Online Therapy for Insomnia Linked to Improved Mental Health

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University students undergoing online CBT program had reductions in insomnia, paranoia, hallucinations
The population-based rate of off-road-vehicle-related injuries was reduced following a 2010 Massachusetts law restricting their use by children aged younger than 14 years and regulating their use by children up to age 18 years

Age Legislation Cuts Off-Road-Vehicle-Related Injury Rate

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Following implementation of legislation, reduction in rate of ER, inpatient discharges for <18-year-olds
A 10-mL 1 percent lidocaine paracervical nerve block reduces pain during intrauterine device insertion

Lidocaine Nerve Block Reduces Pain During IUD Insertion

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Pain score lower among patients who receive lidocaine than those who receive placebo
Height is an independent predictor of venous thromboembolism

Greater Height Tied to Higher Risk of Venous Thromboembolism

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Study using sibling pairs discordant for height reduces chance of familial confounding
Neurological complications associated with anti-programmed death 1 antibody treatment have a diverse phenotype

Diverse Neurological Effects Linked to Anti-PD-1 Therapy

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Complications seen after median of 5.5 cycles of anti-PD-1-inhibitors; include myopathy, neuropathies
Women on antiepileptic drugs during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age infants

Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs

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Increased risk for women on AEDs for epilepsy or other indications; risk varies with drug used
Zika virus is an oncolytic virus that preferentially targets glioblastoma stem cells

Zika Virus Preferentially Targets Glioblastoma Stem Cells

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ZIKV preferentially infects, kills GSCs relative to differentiated tumor progeny, normal neuronal cells
A specific subset of tissue factor-expressing monocytes persist after virological suppression and trigger the coagulation cascade by activating factor X in HIV

In HIV, Tissue Factor-Expressing Monocytes Trigger Coagulation

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The anticoagulant Ixolaris blocked functional activity of tissue factor in vitro and in vivo
Plasma biomarkers that may improve the prediction of rapid decline in renal function in type 2 diabetes have been identified

Biomarkers Can Predict Rapid Drop in Renal Function in T2DM

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ApoA4, CD5L, C1QB, IBP3 may improve prediction of rapid decline in renal function in type 2 diabetes
Psychological and/or educational interventions have a small but significant benefit for anxiety prevention

Preventive Psychological, Educational Programs Beneficial

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Effect size is small, but findings held true across varied populations