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Monthly Archives: July 2017

There is an increased risk of intellectual disability in children whose mothers take antidepressants while pregnant

Link for Maternal Antidepressant, Kids’ Brain Health Questioned

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No significant association for use of antidepressant in pregnancy, child's intellectual disability
The potential first gene therapy in the United States is being reviewed by a U.S. Food and Drug Administration expert panel.

Potential First U.S. Gene Therapy Now Under FDA Review

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Tisagenlecleucel could be a one-time treatment for children and young adults with advanced leukemia
Idarucizumab can reverse the anticoagulant effect of dabigatran in emergency situations

Idarucizumab Shows Reliable Reversal of Dabigatran

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Effective for dabigatran reversal among patients with uncontrolled bleeding, undergoing urgent surgery
In farnesoid X receptor knockout mice

Western Diet Associated With Chronic Hepatic Inflammation

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Western diet-induced dysbiosis in FXR KO mice linked to persistent hepatic inflammation
For older patients receiving prednisolone

Alendronate Cuts Hip Fx Risk in Seniors Taking Prednisolone

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No association for alendronate treatment with risk of mild upper GI symptoms, peptic ulcers
For patients with grass pollen-induced allergic rhinitis

Booster Allergen Immunotx Cuts Symptoms in Allergic Rhinitis

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Ultra-short-course booster AIT prevents symptom recurrence in grass pollen-induced allergic rhinitis
Celiac disease is a common comorbidity in young people with type 1 diabetes

International Variation in Prevalence of Celiac in T1DM

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Overall, 3.5 percent of children had biopsy-confirmed CD; prevalence was higher for girls than boys
Epinephrine administration in children at risk of anaphylaxis often occurs with considerable delay

Too Many Children Not Getting Epinephrine When Needed

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Findings suggest ongoing education for patients and medical care professionals needed
Severely impaired left ventricular global longitudinal strain is associated with worse prognosis in predialysis and dialysis patients

Mortality Up With Impaired LV Global Longitudinal Strain in CKD

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Worse prognosis for patients with severely impaired left ventricular global longitudinal strain
Chest computed tomography is increasingly being used

Chest CT Is Increasingly Being Used in COPD Assessment

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CT can provide information on comorbidities, including coronary artery disease, osteoporosis