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Monthly Archives: June 2017

The methylene tetrahydrofolate reductase (MTHFR) gene A1298C polymorphism does not appear to be related to methotrexate efficacy or toxicity in patients with rheumatoid arthritis

MTHFR A1298C Polymorphism Not Linked to MTX Outcomes in RA

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No significant link for MTHFR gene A1298C polymorphism with methotrexate efficacy, toxicity
Administration of allergen immunotherapy in patients with allergic asthma leads to lower short-term symptom and medication scores

Short-Term Benefits for Immunotherapy in Allergic Asthma

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Reductions seen in short-term symptom scores and medication scores, with evidence of publication bias
Recreational cannabis users are at increased risk of periodontal disease

Recreational Cannabis Negatively Affects Gums When Used Often

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People who use it frequently twice as likely to have periodontal disease, researchers say
Subtle brain changes may explain why some patients with multiple sclerosis lose their ability to interpret social cues

Brain Changes in MS May Contribute to Lack of Empathy

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Diffuse normal-appearing white matter damage may create disconnection in social brain network
Multidrug-resistant gram-negative bacteria

Drug-Resistant Bacteria Seen in Many Nursing Home Residents

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More infection-prevention education and policies are needed, researcher says
Excess weight is associated with increased costs across health care settings

Excess Weight Increases Costs Across Health Care Settings

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Percentage increases in costs associated with obesity were highest for medications, higher for women
An appointment-based model which synchronizes medication refills to improve medication adherence is associated with improvement in medication-taking behavior

Medication Adherence Up With Refill Synchronization Model

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Improvement in medication-taking behavior; cost savings over one year for HTN, DM, hyperlipidemia
A pill containing the antiviral drugs sofosbuvir

Three-Drug Combo Pill Nearly 100 Percent Effective in Curing Hep C

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Pill (sofosbuvir, velpatasvir, voxilaprevir) is for patients who have failed with direct-acting antivirals
Capecitabine (Xeloda) can extend the lives of patients with human epidermal growth factor receptor 2-negative breast cancer who have residual invasive disease after receipt of neoadjuvant chemotherapy

Certain Breast CA Patients Benefit From Adjuvant Capecitabine

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Capecitabine cut risk of relapse, death by 30 percent over five years, researchers say
More Americans with HIV are adhering to antiretroviral therapy regimens

Antiretroviral Regimen Adherence Up for Americans With HIV

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But too many still stop taking drugs a few years after diagnosis