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Monthly Archives: January 2017

After metformin failure

Sequential Empagliflozin, Linagliptin Diabetes Tx Effective

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Glucose control most probably mediated by effects on alpha- and beta-cell function
Physician participation in meaningful use is associated with improvement in colorectal cancer screening

Participation in Meaningful Use Doesn’t Up Quality of Care

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Improvement in colorectal cancer screening but not in other quality of care metrics
Patients with sustained or newly developed cancer cachexia at six and 12 months after initial treatment for advanced head and neck squamous cell carcinoma are at higher risk of cancer recurrences

Cancer Cachexia Associated With Poor Outcomes

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Findings at six and 12 months after treatment for advanced head and neck cancer
The activity of certain genes are associated with premenstrual dysphoric disorder

Sex Hormone-Sensitive Gene Complex Implicated in PMDD

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Study adds to evidence of a biological cause of condition, researchers say
The Zika virus is not likely to gain a foothold in the United States as it did in Brazil and other Latin American countries

Major Zika Outbreak Considered Unlikely in the United States

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Higher standard of living reduces odds the virus-carrying mosquitoes will thrive
For patients who have undergone percutaneous coronary intervention

No Lasting Benefit for Follow-Up Coronary Angiography After PCI

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No difference in cumulative five-year incidence of primary end point, any coronary revascularization
Social contagion accounts for a considerable proportion of gunshot violence episodes

Gunshot Violence Transmitted Through Social Networks

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Best performing models for predicting victims of gun violence based on social contagion, demographics
Use of zoledronic acid every 12 weeks does not result in increased risk of skeletal events compared with use every four weeks among patients with bone metastases due to breast cancer

Zoledronic Acid Every 12 Weeks Noninferior in Bone Metastases

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No increase in risk of skeletal events versus treatment every four weeks for bone metastases
Conventional clinical trials are unable to detect clinically important heterogeneity in intensive blood pressure treatment effects

Conventional Trials Can’t Detect Heterogeneity in BP Tx Effects

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Clinically important heterogeneity in intensive BP tx effect can be ID'd in sequential randomization trials
The American College of Physicians has updated recommendations on the oral pharmacologic treatment of type 2 diabetes in adults. The clinical practice guideline update was published online Jan. 3 in the Annals of Internal Medicine.

ACP Updates Recommendations for Oral Medications in T2DM

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Recs serve as update to 2012 American College of Physicians guideline