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Monthly Archives: November 2016

Tailored dose-dense chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer

Dense-Dose Chemo of Little Benefit in Early Breast Cancer

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No statistically significant improvement found in breast cancer recurrence-free survival
High-frequency electrical stimulation of the spinal cord may relieve severe chronic back pain more effectively than conventional low-frequency stimulation

High-Frequency Spine Stimulation Offers Superior Pain Relief

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Helps block pain signals better than low-frequency treatments for chronic back and leg pain
Lipid-rich necrotic core in the proximal superficial femoral artery is associated with higher rates of peripheral artery disease events

Lipid-Rich Necrotic Core in Femoral Artery Ups PAD Events

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Association, seen in patients with peripheral artery disease, was independent of ankle brachial index
Only about half of U.S. family doctors follow guidelines on screening patients for prediabetes

Prediabetes Screening Guidelines Not Always Followed by PCPs

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They split 50-50, survey shows, on advice aimed at preventing progression to diabetes
For patients with infantile hemangiomas

U/S IDs Response to Propranolol in Infantile Hemangioma

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Serial ultrasonography can be used to demonstrate response to treatment with propranolol
In the past decade

Self-Harm Now a Leading Cause of Pregnancy-Related Mortality

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Findings based on records of maternal deaths in Colorado between 2004 and 2012
Hospitalized children have reduced survival odds with cardiopulmonary resuscitation events occurring at night compared to other times of the day

Survival Lower for Night CPR Events in Children

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Pediatric CPR events at night tied to 12 percent reduced odds of survival
Increased body mass index may have a moderate effect on hand arthritis

Meta-Analysis Links Increased BMI, Hand Osteoarthritis

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Weak but significant effect seen on risk of radiographic hand osteoarthritis
Patients with multiple areas of dysplastic squamous epithelium have increased risk for metachronous squamous cell carcinomas in the upper aerodigestive tract

Multiple Dysplastic Lesions in Esophagus Up Risk of SCC

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Increased risk of multiple squamous cell carcinomas in esophagus and head and neck
Macrophage cyclooxygenase-2 deletion is associated with progression of diabetic nephropathy

Macrophage COX-2 Prevents Diabetic Nephropathy Progression

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Mice with COX-2 deletion in hematopoietic cells or macrophages have severe DN vs WT diabetic mice