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Monthly Archives: August 2016

Women with vaginal mesh with complications have a significantly increased proinflammatory response

Proinflammatory Response in Women With Vaginal Mesh

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Significantly higher M1/M2 cytokines, chemokines, MMP-9 and -2 in women with mesh-vagina explants
Opioid users may be misusing and abusing gabapentin

Some Opioid Users May Be Taking Gabapentin Without an Rx

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Findings reveal need for more robust testing
The number of private health insurance claims for Americans addicted to opioids and heroin rose 3

Opioid-Related Insurance Claims Rise 3,000 Percent

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Present crisis disproportionately affecting white, middle-class people in non-urban settings
Sickle cell trait is not associated with a higher risk of death than absence of the trait

Sickle Cell Trait Doesn’t Up Mortality Risk in U.S. Soldiers

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However, SC trait was linked with significantly higher risk of exertional rhabdomyolysis
Government spending on compounded drugs has skyrocketed

Spending on Compounded Drugs Skyrocketing

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Number of Medicare beneficiaries getting compounded drugs up 281 percent since 2006
Two novel loci have been identified that are associated with insulin sensitivity

Study IDs Two Novel Loci Linked to Insulin Sensitivity

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Associations for BCL2 and FAM19A2 were independent of known cardiometabolic loci
Among adults with septic shock

Vasopressin Doesn’t Cut Kidney Failure-Free Days in Septic Shock

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No improvement in kidney failure-free days versus norepinephrine in adults with septic shock
An off-site central monitoring unit applying standardized cardiac telemetry is associated with detection and notification of cardiac rhythm and rate changes before emergency response team activation

Standardized Cardiac Telemetry IDs Cardiac Rhythm Change

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Use of telemetry with off-site central monitoring unit linked to detection of cardiac rhythm, rate changes
Targeted therapies that do not contain erlotinib can be beneficial for patients with KRAS-mutated advanced non-small-cell lung cancer

Targeted Therapies Beneficial in KRAS-Mutated NSCLC

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Improved progression-free survival for patients treated with therapy not containing erlotinib
Topical application of BRAF inhibitors may accelerate healing of skin wounds

BRAF Inhibitors May Accelerate Wound Healing

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Topical application with vemurafenib accelerated wound healing via paradoxical MAPK activation