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Monthly Archives: August 2016

Patients with nonfunctional adrenal tumors have increased risk of diabetes compared to those without adrenal tumors

Increased Risk of Diabetes With Nonfunctional Adrenal Tumors

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Increased risk of incident composite diabetes compared to those without adrenal tumors
For patients with hidradenitis suppurativa

Adalimumab Effective for Hidradenitis Suppurativa

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Findings from two phase 3 trials show increased clinical response rates compared with placebo
The Amish environment seems to provide protection against asthma and allergic sensitization

Amish Farm Environment May Protect Children From Asthma

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Amish, Hutterite children have profound differences in proportions, phenotypes, functions of immune cells
Tumor cell-intrinsic metabolic factors may contribute to anti-programmed death 1 (PD-1)/PD-L1 treatment resistance in renal cell carcinoma

Metabolic Factors May Contribute to Tx Resistance in Renal Cancer

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Genes involved in metabolic and solute transport function linked to treatment failure in PD-L1+ RCC
Nonablative radiofrequency treatment can improve skin elasticity around the eye area

Nonablative Radiofrequency Tx Ups Skin Elasticity Around Eyes

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Treatment improves skin elasticity in cutometrical analysis; improvement noted on photodocumentation
The cytokine M-CSF promotes survival of lung and liver mononuclear phagocytes to mediate host defense during bacterial pneumonia

M-CSF Plays Role in Host Defense in Bacterial Pneumonia

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M-CSF promotes survival of lung and liver mononuclear phagocytes in experimental model
A parsimonious patient-level clinical risk model can predict in-hospital mortality for patients with acute myocardial infarction

Patient-Level Model Predicts In-Hospital Mortality in Acute MI

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Parsimonious model predicts mortality, with C-statistic of 0.88 and good calibration
An often quoted standard panel size of 2

Panel Size of 2,500 Patients Per Doc Not Feasible in Primary Care

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Anecdotal panel size incompatible with provision of adequate patient care
C-peptide responses to mixed-meal tolerance tests are reliable surrogates of insulin secretion

C-Peptide Responses Reliable Surrogates of Insulin Secretion

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Expected inverse relationships between C-peptide and HbA1c, insulin dose vary over time, with age
More Medicaid-covered children are receiving treatments that conform to practice standards for attention-deficit/hyperactivity disorder

Increase in Evidence-Based Practice for Children With ADHD

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Findings based upon publicly-insured children from 2001 to 2010