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Men who have sex with men receiving antiretroviral therapy to treat HIV infection may be at increased risk for syphilis

Syphilis Risk May Be Higher in HIV Patients on Antiretrovirals

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Medications may raise susceptibility to bacterium that causes the sexually transmitted disease
Ocular syphilis has been identified in jurisdictions in the United States

Ocular Syphilis Cases May Be Increasing in United States

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Among total syphilis surveillance cases in eight jurisdictions, 0.65 percent indicated ocular symptoms
Skin biopsies from patients co-infected with HIV and syphilis have moderate to extensive lymphoplasmacytic infiltrate

Lymphoplasmacytic Infiltrate Seen in Syphilis, HIV Co-Infection

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Skin biopsies show moderate to extensive infiltrate; quantity of treponemes linked to CD4 count
The U.S. Preventive Services Task Force recommends screening for syphilis infection in non-pregnant persons who are at increased risk of infection. These findings form the basis of a recommendation statement published in the June 7 issue of the Journal of the American Medical Association.

USPSTF Recommends Screening for Syphilis Infection

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Grade A recommendation for screening in non-pregnant persons at increased risk of infection
A case of acquired syphilis leading to involvement of the bone marrow and liver is described in a report published online March 22 in the Annals of Internal Medicine.

Report of Bone Marrow/Liver Pathology Caused by Syphilis

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Case study describes 65-year-old patient with late-latent syphilis with normocytic anemia
All adults and teens at increased risk for syphilis should be screened for the sexually transmitted disease

USPSTF: Screen All Teens, Adults at Risk for Syphilis

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Proposed recommendation dovetails with surge in U.S. cases of the sexually transmitted disease
Congenital syphilis cases increased 38 percent between 2012 and 2014

CDC: Sharp Increase in U.S. Babies Born With Syphilis

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Of infected babies born in 2014, 15 percent of mothers were never tested for syphilis
Universal third-trimester syphilis rescreening is not cost-effective given the national average seroconversion rate

Universal 3rd-Trimester Syphilis Rescreening Not Cost-Effective

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19-fold higher seroconversion incidence for universal rescreening to be cost-effective
Health care providers on the West Coast need to look out for syphilis that can cause blindness

Health Officials Warn of Blinding Cases of Syphilis on West Coast

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Doctors and eye-care providers should be alert for symptoms of ocular syphilis
A smartphone accessory that can detect HIV and syphilis has been developed by Columbia University researchers. The findings were published in the Feb. 4 issue of Science Translational Medicine.

Smartphone Accessory Could Help Detect HIV, Syphilis

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Low-cost accessory replicates laboratory-based blood test, researchers report