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Guidelines have been developed for perioperative management of antirheumatic drug therapy in patients with rheumatic diseases undergoing elective total hip arthroplasty or total knee arthroplasty; the guidelines were published online June 16 in Arthritis Care & Research.

Guidelines Address Peri-Op Care in Rheumatic Disease

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Guidelines address use of antirheumatic drugs for adults with RA, SpA, JIA, SLE undergoing THA/TKA
Tofacitinib is associated with improvements in nail psoriasis

Tofacitinib Associated With Improvement in Nail Psoriasis

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Improvement in nail psoriasis severity at 16 weeks versus placebo; maintained through 52 weeks
Pimecrolimus 1 percent cream applied twice a day for four weeks seems to be the best regimen for patients with facial seborrheic dermatitis

Month of BID Pimecrolimus Best in Facial Seborrheic Dermatitis

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Most improvement in total severity score for pimecrolimus 1% cream twice daily for four weeks
Health insurers are recruiting former pharmaceutical company representatives to educate doctors and help save money on prescription medications

Health Insurers Recruiting Former Pharma Reps to Cut Costs

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Former pharma reps are educating doctors about costs of meds, encouraging use of generics
For patients in an urban clinic with hepatitis C virus (HCV) with HIV coinfection

High HCV Cure Rates in HIV Coinfection Cases at Urban Clinic

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Sustained virologic response rate of 97 percent, with no variation by race in predominantly black cohort
The American Medical Association is calling for more transparency in drug pricing amid rising costs that are putting some lifesaving medications out of reach for patients and communities.

AMA Endeavors to Increase Transparency of Rx Pricing

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At annual meeting, the physicians' group adopted new policies on drug pricing to protect patients
In prepubertal

Metformin Tied to Decreased BMI z Score in Prepubertal Children

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Notable increments also seen in quantitative insulin sensitivity check index, adiponectin-leptin ratio
For patients with HIV with talaromycosis

Amphotericin Tops Itraconazole in HIV-Linked Talaromycosis

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Reduced risk of death at six months, faster clinical resolution and fungal clearance versus itraconazole
For patients with heart failure with reduced ejection fraction in sinus rhythm

Beta-Blockers Cut Mortality for Patients in Sinus Rhythm

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Drop in mortality for patients with heart failure with reduced ejection fraction regardless of heart rate
Among high-risk patients with type 2 diabetes

ADA: Degludec Noninferior for Cardiovascular Events in T2DM

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Noninferior to glargine for incidence of major cardiovascular events in high-risk patients with T2DM