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For cases of mild atrial fibrillation-related acute ischemic stroke

Warfarin, Rivaroxaban Similarly Safe, Effective

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Findings among cases of mild atrial fibrillation-related acute ischemic stroke
Adjuvant therapy with nivolumab is associated with longer recurrence-free survival than therapy with ipilimumab among patients undergoing resection of stage IIIB

Adjuvant Nivolumab Tops Ipilimumab in Melanoma

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Longer recurrence-free survival for stage IIIB, IIIC, IV melanoma
Patients with chronic obstructive pulmonary disease with an eosinophilic phenotype may benefit from mepolizumab

Mepolizumab Beneficial in COPD With Eosinophilic Phenotype

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Lower annual rate of moderate, severe exacerbations for patients receiving 100 mg mepolizumab
For patients with resected stage III melanoma with BRAF V600E or V600K mutations

Dabrafenib, Trametinib Beneficial in Resected Melanoma

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Rate of relapse-free survival up for resected stage III melanoma with BRAF V600E, V600K mutations
Women on antiepileptic drugs during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age infants

Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs

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Increased risk for women on AEDs for epilepsy or other indications; risk varies with drug used
For patients with locally advanced

Longer Progression-Free Survival for Durvalumab in NSCLC

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Longer median progression-free survival from randomization, higher response rate with durvalumab
The median cost of cancer drug development is $648.0 million

Median Cost of Cancer Drug Development $648.0 Million

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Total revenue from sales of 10 drugs was $67.0 billion, with total R&D spending of $7.2 billion
Romosozumab treatment followed by alendronate is linked to reduced risk of fractures versus alendronate alone for postmenopausal women with osteoporosis

ASBMR: Romosozumab Reduces Fracture Rate in Osteoporosis

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Reduced risk of new vertebral fractures, nonvertebral fractures for romosozumab and alendronate
Alendronate treatment reduces the risk of hip fracture in elderly patients with a prior fracture

Alendronate Effective, Safe in ‘Oldest Old’ With Prior Fracture

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Alendronate treatment reduced risk of hip fracture with sustained safety
Tiotropium appears to be effective at improving lung function in patients with mild to moderate chronic obstructive pulmonary disease

Tiotropium Effective in Mild to Moderate COPD

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Daily inhaled dose tied to improvements in FEV1 compared to placebo