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For patients with super-refractory status epilepticus

Brexanolone Tolerated in Super-Refractory Status Epilepticus

Associated with high rate of third-line agent weaning; no serious adverse events attributed to the drug
Several significant interactions can occur between cannabidiol and antiepileptic drugs

Interactions Occur With Cannabidiol, Antiepileptic Drugs

Most observed mean level changes fall within accepted therapeutic range
For men with nonmetastatic prostate cancer who are receiving androgen deprivation therapy

Osteoporosis Meds Up BMD in Nonmetastatic Prostate Cancer

Review shows improved bone mineral density in men receiving androgen deprivation therapy

mAb Glucagon Receptor Blocker Suitable for Further Development

REGN1193 inhibited glucose increase stimulated by glucagon in dose-dependent manner

Ipragliflozin Beneficial in T2DM Complicated by Liver Disease

Effect similar to pioglitazone, with reduction in body weight, abdominal fat only for ipragliflozin

Genetic Variation Impacts Pharmacokinetics of Exemestane

Significant differences in plasma exemestane area under the curve for OATP1B1 genotype groups

In Utero Psychotropics + Opioids Up Neonatal Drug Withdrawal

Risk of withdrawal increased two-fold with in utero exposure to two or more psychotropics plus opioids

APA: Reasons for Underuse of Buprenorphine by PCPs ID’d

Doctors not willing to increase prescribing due to lack of belief in agonist tx, lack of time for more patients

Canagliflozin Delays Increase in Certain CV Biomarkers in T2DM

Canagliflozin may reduce CV, heart failure risk over two years versus placebo in older patients with T2DM

ABP 501, Adalimumab Biosimilar, Safe and Effective, for Psoriasis

Findings based on comparison over 52 weeks, including single transition