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Almost half of elderly patients newly diagnosed with acute lymphoblastic leukemia do not receive treatment

Only About Half of Elderly Newly Diagnosed With ALL Receive Tx

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53.5 percent receive treatment within 90 days; 32.4 percent receive chemo without tyrosine kinase inhibitors
For hyperphosphatemic patients with chronic kidney disease receiving maintenance hemodialysis

Tenapanor Reduces Elevated Serum Phosphate in CKD

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Adverse events limited to softened stool, modest increase in bowel movement freqeuncy
The U.S. Food and Drug Administration on Tuesday approved the nasal spray medication esketamine -- a relative of the club drug and anesthetic ketamine -- for use against severe depression. Sold as Spravato

FDA Approves Ketamine-Like Drug for Severe Depression

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Drug available through restricted distribution system, must be administered in certified medical office
In 2016

About 360,000 ED Visits Were for Nonmedical Drug Abuse in 2016

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More than half of estimated visits also involved nonpharmaceutical substances, including drugs, alcohol
For patients with multiple actinic keratosis lesions on the head

Fluorouracil Cream Best Choice for Tx of Actinic Keratosis Lesions

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Fluorouracil more effective than imiquimod, methyl aminolevulinate photodynamic tx, ingenol mebutate
A series of interventions introduced through a quality improvement project can increase the frequency of both teratogen education and urine pregnancy screening in patients taking teratogenic medications for rheumatic disease

Program in Peds Rheumatology Clinic Ups Education on Teratogenic Rx

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Findings seen among girls, women of childbearing age prescribed teratogenic meds
An iterative

Multidimensional Approach Cuts Unneeded Drug-Drug Interaction Alerts

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Number of interruptive DDI alerts substantially decreased as result of alert refinement efforts
For patients with acne

AAD: Isotretinoin Exposure for Acne Not Linked to Depression Risk

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Acne patients with, without isotretinoin exposure had no significant difference in depression frequency
A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans

FDA Warns Americans Not to Buy Drugs From Canadian Company

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CanaRx sells prescription medicines at a lower cost to U.S. public, private employer programs
A safety clinical trial has revealed that tofacitinib (Xeljanz

FDA: Pulmonary Embolism Risk Up With Tofacitinib 10 mg for RA

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Safety clinical trial shows risk for PE, death with 10-mg dose versus 5-mg dose, TNF inhibitor