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Cardiovascular adverse drug reactions occur in association with ibrutinib

Severe Adverse Cardiovascular Events Associated With Ibrutinib

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Risk up for severe, sometimes fatal, events, including supraventricular arrhythmias, CNS events
In contrast to findings in black adolescents and adults

Step-Up Strategy May Differ in Black Children With Asthma

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Poorly controlled asthma in black children may respond to increased dose of inhaled glucocorticoid
In moderate-to-severe ulcerative colitis

Vedolizumab Beats Adalimumab for Ulcerative Colitis Remissions

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But not for corticosteroid-free clinical remission; also, ustekinumab superior to placebo
The recall of the commonly prescribed blood pressure drug losartan has been expanded once again to include an additional five lots.

More Blood Pressure Drugs Recalled

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Some lots of losartan contaminated with the cancer-causing chemical N-methylnitrosobutyric acid
For patients with heart failure and reduced ejection fraction

Dapagliflozin Lowers Risk for Worsening Heart Failure

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Findings seen among patients with heart failure, reduced ejection fraction, irrespective of diabetes
Use of sodium glucose cotransporter 2 inhibitors for type 2 diabetes is associated with a reduced risk for heart failure

SGLT2 Inhibitors Linked to Lower Risk for Heart Failure

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Risk lower for HF, but not major CV events, compared with new users of DPP4 inhibitors
Considerable racial/ethnic disparities exist in HIV preexposure prophylaxis awareness

Racial/Ethnic Disparities Seen in PrEP Awareness, Discussions

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Black and Hispanic men who have sex with men less likely to be aware, have discussed PrEP than whites
Linagliptin is noninferior to glimepiride for adults with relatively early type 2 diabetes and elevated cardiovascular risk

Linagliptin Noninferior for CV Risk in Early Type 2 Diabetes

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Linagliptin compared with glimepiride for risk for major cardiovascular events in T2DM with elevated CV risk
Treatment with metformin versus sulfonylureas is associated with a reduced risk for major adverse cardiovascular events among patients with type 2 diabetes and reduced kidney function

CV Risk Lower With Metformin in T2DM + Reduced Kidney Function

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Risk for major adverse cardiovascular events reduced with metformin compared with a sulfonylurea
House Speaker Nancy Pelosi has revealed a plan to lower the cost of medications for people on Medicare and those with private insurance.

House Speaker Unveils Plan to Lower Drug Costs

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Plan would allow Medicare to negotiate prices for high-cost drugs