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Ibrutinib is associated with an increased risk for new or worsened hypertension in patients treated for B-cell malignancies

Ibrutinib Therapy Linked to New, Worsened Hypertension

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Ibrutinib-related hypertension associated with increased risk for major adverse cardiovascular events
After one year of therapy with lumacaftor-ivacaftor in a real-world setting

Lumacaftor-Ivacaftor Aids Cystic Fibrosis in Real-World Setting

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Improved lung function, increased BMI, reduced need for IV antibiotics seen after one year of therapy
A class of diabetes drugs

SGLT2 Inhibitors Protect Against Kidney Disease in T2DM

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Reduction seen for risk of dialysis, transplantation, or death due to kidney disease
The poly(adenosine diphosphate-ribose) polymerase inhibitor veliparib plus platinum-based chemotherapy for induction therapy

PARP Inhibitor Slows Progression of Advanced Ovarian Cancer

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Veliparib added to chemotherapy, continued as maintenance tx prolongs progression-free survival
Hydroxychloroquine blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus

Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus

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Prospective cohort study demonstrates link between HCQ blood levels and retinopathy risk
Over-the-counter medications are commonly used in suicide attempts by self-poisoning among young people

OTC Meds Often Used in Drug-Related Suicide Attempts in Youth

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ADHD meds commonly used by those aged 10 to 15 years, while sedative/hypnotics used more by older youth
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

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Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy
The addition of abemaciclib to fulvestrant provides a statistically significant and clinically meaningful gain in median overall survival

Drug Combo Extends Survival in Advanced Breast Cancer

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Benefit seen for addition of CDK4/6 inhibitor after progression of disease on endocrine therapy
Ligelizumab appears to be a safe and effective treatment option for chronic spontaneous urticaria

Ligelizumab Safely, Effectively Treats Hives

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Doses of 72 mg or 240 mg tied to complete control of symptoms after 12-week trial
A three-in-one inhaler therapy can improve lung function and reduce asthma attacks in adults with uncontrolled disease

Three-Drug Single Inhaler Treats Uncontrolled Asthma in Adults

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Findings seen in two large international clinical trials comparing three-drug inhaler to two-drug inhaler