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Uptake of guideline-directed preventive therapies is lower for patients with stroke and peripheral artery disease compared with those with coronary artery disease

Statin, Aspirin Uptake Low With Peripheral Artery Disease, Stroke

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Authors call for increased awareness of need for treatment with secondary preventive medications
Treating hospitalized COVID-19 patients with hydroxychloroquine

Hydroxychloroquine No Aid for COVID-Related Mortality

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Hydroxychloroquine alone or with azithromycin associated with abnormal electrocardiogram findings
For patients with metastatic urothelial carcinoma

Addition of Atezolizumab May Aid in Metastatic Urothelial Cancer

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Phase 3 trial shows prolonged progression-free survival for atezolizumab plus platinum-based chemo
Interferon-α2b therapy seems to shorten the duration of viral shedding in hospitalized COVID-19 patients

Interferon-α2b May Shorten Viral Shedding Duration in COVID-19

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Duration of elevated blood levels for inflammatory markers IL-6, C-reactive protein also reduced
In a special article from the American College of Physicians

ACP Advises Against Chloroquine, Hydroxychloroquine for COVID-19

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Practice points based on lack of evidence supporting use as prophylaxis or treatment for COVID-19
The National Institute of Allergy and Infectious Diseases announced it is sponsoring a phase 2b clinical trial to evaluate the efficacy and safety of hydroxychloroquine and azithromycin in preventing hospitalization and death from COVID-19.

NIH Launches Trial of Hydroxychloroquine, Azithromycin for COVID-19

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Trial will enroll 2,000 patients with SARS-COV-2 who have fever, cough, and/or shortness of breath
Atezolizumab plus bevacizumab improves survival outcomes versus sorafenib in patients with unresectable hepatocellular carcinoma

Atezolizumab-Bevacizumab Beats Sorafenib in Liver Cancer

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Overall, progression-free survival longer with combo in unresectable hepatocellular carcinoma
For women with bacterial vaginosis

Live Biotherapeutic Promising for Prevention of Bacterial Vaginosis

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Following vaginal metronidazole for BV, incidence of recurrence lower with Lactin-V versus placebo
For pediatric patients with acute myeloid leukemia

Dexrazoxane Preserves Cardiac Function in Pediatric Leukemia

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Beneficial for patients with AML receiving anthracyclines, with no impact on event-free, overall survival
Among patients with heart failure

For Those With Heart Failure, ACE2 Concentrations Up in Men

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Use of ACE inhibitors, ARBs not tied to higher plasma ACE2 concentrations in those with heart failure