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For patients with knee osteoarthritis

Physical Therapy, Lifestyle Advice Underused in Knee OA

2007 to 2015 saw increase in use of NSAID prescriptions from orthopedists, primary care doctors
Among individuals aged 66 years and older

Suicide Risk Up With ARB Exposure Versus ACEI Exposure

Risk for suicide increased with angiotensin receptor blockers among individuals aged 66 years and older
Most office-based physicians who provide sexually transmitted infections services report not having on-site access to the recommended injectable medications for same-day treatment of gonorrhea and syphilis

Most Physicians Treating STIs Do Not Have Meds on Hand

Increasing availability of treatments will help public health officials stop increases in STIs, authors say
Patients with primary restless leg syndrome who begin dopamine agonist therapy may be at increased risk for adverse psychiatric events

Dopamine Agonists Tied to Higher Risk for Psychiatric Events

Findings seen in large study of patients with restless leg syndrome starting dopamine agonists
Tesamorelin reduces liver fat content in patients with HIV and nonalcoholic fatty liver disease

Tesamorelin May Aid Patients With HIV, Fatty Liver Disease

Tesamorelin significantly reduced hepatic fat fraction compared with placebo
Most dimensions of quality of life (QoL) are impaired in patients with relapsed/refractory multiple myeloma

Effects on Quality of Life Mixed for Tx of Multiple Myeloma

Reduced pain but worsening of neuropathy seen for IxaThalDex induction tx in relapsed/refractory MM
Ibrutinib is associated with an increased risk for new or worsened hypertension in patients treated for B-cell malignancies

Ibrutinib Therapy Linked to New, Worsened Hypertension

Ibrutinib-related hypertension associated with increased risk for major adverse cardiovascular events
After one year of therapy with lumacaftor-ivacaftor in a real-world setting

Lumacaftor-Ivacaftor Aids Cystic Fibrosis in Real-World Setting

Improved lung function, increased BMI, reduced need for IV antibiotics seen after one year of therapy
A class of diabetes drugs

SGLT2 Inhibitors Protect Against Kidney Disease in T2DM

Reduction seen for risk of dialysis, transplantation, or death due to kidney disease
The poly(adenosine diphosphate-ribose) polymerase inhibitor veliparib plus platinum-based chemotherapy for induction therapy

PARP Inhibitor Slows Progression of Advanced Ovarian Cancer

Veliparib added to chemotherapy, continued as maintenance tx prolongs progression-free survival