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Cell-free DNA sequencing represents an advance in genomic medicine and has associated ethical challenges

Review Addresses Cell-Free DNA Sequencing in Pregnancy

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cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing
Higher rates of β-blocker use are seen among women with preeclampsia and asthma

Labetalol Use Up for Patients With Preeclampsia and Asthma

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Use of labetalol versus other antihypertensives linked to increased risk of status asthmaticus
Prenatal tetanus

Prenatal Tdap Vaccination Not Linked to Autism Risk

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No increased risk of autism spectrum disorder in association with prenatal Tdap vaccination
More than half of women who have a baby during surgical residency express some type of career dissatisfaction

Childbearing Surgical Residents Often Feel Career Dissatisfaction

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Perceived pregnancy stigma, no formal maternity leave, altered training tied to dissatisfaction
Opioid use disorder rates at delivery more than quadrupled nationally from 1999 to 2014

CDC: Rates of Opioid Use Disorder Seen at Time of Delivery Up

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Rate of opioid use disorder at time of delivery quadrupled from 1999 to 2014
Maternal vitamin D supplementation from mid-pregnancy until birth or until six months postpartum does not improve fetal or infant growth

Vit D Supplementation Doesn’t Improve Fetal, Infant Growth

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Findings based on study of Bangladeshi women and infants, a population with known deficiency
Uniform application of gestational diabetes mellitus diagnostic thresholds may not be appropriate in populations across the world

Single Threshold May Not Be Feasible for Gestational Diabetes

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Diagnostic thresholds should be adapted using local populations, authors say
Very low-quality evidence supports screening for elevated bacteria levels in urine during the first trimester for non-symptomatic pregnant women

Weak Recommendation to Screen for Bacteriuria in Pregnancy

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Canadian guideline addresses asymptomatic, low-risk pregnant women during the first trimester
Acute myocardial infarction occurred in one of every 12

2002 to 2014 Saw Hike in AMI Rate in Pregnancy, Puerperium

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Rate of acute myocardial infarction one per 12,400 for those hospitalized during pregnancy, puerperium
There have been 11 lung-related infant deaths after pregnant women in the Netherlands were given sildenafil (Viagra) to boost the growth of their babies while in the womb.

11 Infant Deaths Halt Trial of Sildenafil in Pregnant Women

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Aim of the trial was to improve blood flow to the placenta and promote fetal growth