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Prenatal marijuana use increased from 2009 to 2016 for pregnant women of all ages

2009 to 2016 Saw Increase in Prenatal Marijuana Use

Greatest increases seen for pregnant females aged younger than 18 years, those aged 18 to 24 years
Children born to mothers with rheumatoid arthritis may have an increased risk of rheumatoid arthritis

RA Exposure In Utero Tied to Increased Disease Risk

Children exposed to maternal rheumatoid arthritis have higher risk of thyroid disease, epilepsy, RA
Anaphylaxis is a rare complication of pregnancy

Anaphylaxis Is Rare Complication of Pregnancy

Estimated incidence is 1.6 per 100,000 maternities; often the result of a reaction to antibiotics
The majority of both high-risk and intermediate-risk women prefer a non-invasive cell-free prenatal DNA screening as a secondary screening test for trisomy 21

Majority of Women Prefer Non-Invasive Testing for Trisomy 21

Yet, roughly one-third still want an invasive secondary test plus chromosomal microarray
Intrauterine exposure to methylphenidate is associated with a small increase in the risk of cardiac malformations

In Utero Methylphenidate Exposure Tied to Heart Defects

Intrauterine exposure linked to small increase in risk of cardiac malformations based on U.S., Nordic data
Prenatal vitamin D supplementation during pregnancy may have some benefits

Evidence Lacking for Prenatal Vitamin D Supplementation

Although linked to increased mean birth weight, reduced risk of SGA
Coffee consumption seems safe and is associated with reduced risk for various health outcomes

Coffee Consumption Appears to Provide More Benefit Than Harm

Largest relative reduction in health outcomes seen with intake of three to four cups/day versus none
For women undergoing assisted reproductive treatment

Vitamin D Tied to Better Assisted Reproductive Therapy Outcomes

Women replete in vitamin D more likely to have live birth, positive pregnancy test, clinical pregnancy
Exposure to attention-deficit/hyperactivity disorder medication during pregnancy is associated with increased risk of neonatal morbidity

Prenatal Exposure to ADHD Meds Tied to Neonatal Morbidity

Increased risk of neonatal morbidity, especially central nervous system-related disorders
The relative risk of a seizure disorder after eclampsia is higher than that of women unaffected by eclampsia but remains extremely low

Eclampsia Tied to Increased Relative Risk of Seizure Disorder

However, the risk remains extremely low, at 4.58/10,000 person-years