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Spinal Manipulative Therapy for Low Back Pain Tied to Lower Risk for Opioid Use...

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Findings seen for adult patients followed for two years compared with those prescribed ibuprofen for low back pain

Seizure Risk Up for Seniors in Nursing Homes Prescribed Tramadol and Antidepressants

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Risk for seizures increased with concomitant use of tramadol with CYP2D6-inhibiting versus neutral antidepressants

Declines Seen in New, Additional Prescribing of Opioids in Patients With Cancer

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New opioid prescribing was stable for patients with metastatic cancer with pain and declined for those reporting no pain

Receipt of Meds for Opioid Use Disorder in Jail Increases Use After Release

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Receipt of MOUD in jail linked to lower postrelease risks for fatal overdose, nonfatal overdose, reincarceration

High Exposure to Prenatal Prescribed Opioid Analgesics Likely Not Associated With ASD Risk

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Associations were largely or fully attenuated using designs other than accounting for measured confounders and in sibling comparisons

Potentially Inappropriate Medications Linked to Frailty at Cancer Diagnosis

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Each additional Geriatric Oncology-PIM linked to 66 percent increase in odds of being mildly, moderate-to-severely frail at diagnosis

Timely Opioid Administration Cuts Hospitalizations for Pediatric Sickle Cell Crises

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Findings seen for first administration within 60 minutes for children presenting to the emergency department with a sickle cell crisis

FDA Releases Guidance to Promote Nonopioid Alternatives for Chronic Pain

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New guidance aims to increase nonopioid choices for chronic pain while combating misuse

One in 10 Undergoing Early Cancer Surgery Have New Persistent Opioid Use

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Persons in the highest quartile of morphine milligram equivalents exposure have increased risk for new persistent opioid use

Buprenorphine Available at 39.4 Percent of U.S. Pharmacies in 2023

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Increases in availability seen across neighborhood types, but pharmacies located in Black, Latinx neighborhoods less likely to dispense