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Metabolic Surgery Has Greater Long-Term Benefits Than GLP-1 Receptor Agonists

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Findings seen for long-term outcomes among adult patients with diabetes and obesity

Patients With Extreme Obesity Face Limitations to Accessing Specialty Care

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41 percent of practices declined to schedule appointment for hypothetical patient weighing 465 lb; 52 percent lacked basic standards of care

Oral Semaglutide Effective for Weight Loss in Overweight or Obesity

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Estimated mean change in body weight from baseline to week 64 was −13.6 and −2.2 percent with oral semaglutide and placebo, respectively

Oral Orforglipron Yields Greater Weight Reductions Than Placebo

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Significant mean change in body weight from baseline to week 72 seen with various dosages of orforglipron compared with placebo among adults with obesity

GLP-1 Receptor Agonists Improve Glycemic, Weight Outcomes in Children With T2D

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Glycemic, weight, cardiometabolic outcomes improved for children and teens with obesity, prediabetes, or T2D

Once-Weekly Semaglutide 7.2 mg Beats Placebo for Obesity

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Second study shows 7.2 mg semaglutide leads to greater reductions in mean body weight for those with obesity, T2D

Weight-Loss Surgery Bests Medical Weight Management for Obesity-Related Risk Mitigation

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Significantly lower risk seen for developing major metabolic comorbidities

GLP-1 RAs Cost-Effective Versus Usual Care for Knee OA, Obesity

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Tirzepatide offers more favorable return on investment, but greater benefits seen at lower costs for Roux-en-Y gastric bypass

Without Biannual Time Shift, Prevalence of Obesity, Stroke May Be Reduced

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Modeling study shows decrease in prevalence of both obesity and stroke under Standard Time, Daylight Saving Time versus current policy

Parent-Focused Interventions Do Not Prevent Obesity at Age 24 Months

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Review and meta-analysis show parent-focused interventions insufficient for preventing obesity in young children