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The eradication of malaria worldwide may eventually be possible

WHO: Malaria Eradication Not Currently Possible

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Smallpox the only human disease to ever have been wiped out
Malawi has become the first country to start immunizing children against malaria

Malawi First Country to Immunize Children Against Malaria

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The vaccine, called Mosquirix, was approved by the European Medicines Agency in 2015
The drug artesunate -- the World Health Organization-recommended first-line treatment for severe malaria -- will become the first-line treatment for severe malaria in the United States

Guidance Lists New First-Line Treatment for Severe Malaria in the U.S.

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With discontinuation of quinidine, IV artesunate is now first-line drug for treatment of malaria
For adults with acute Plasmodium vivax or P. falciparum

KAF156 Active for Adults With Vivax, Falciparum Malaria

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Antimalarial activity seen with multiple and single dose, with no serious adverse events
The world's most promising malaria vaccine (RTS

Malaria Vaccine Protection Short-Lived in Young Children

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Children in study were given three doses, but manufacturer now says four doses needed
Plasmodium falciparum gene Kelch (K13)-propeller sequence polymorphism analysis can assist with surveillance of artemisinin resistance

K13 Polymorphism Analysis Can ID Resistance Mutations

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Mutations in P. falciparum K13 show marked geographic disparity in frequency and distribution
The incidence of transfusion-transmitted malaria can be reduced with use of a whole blood pathogen-reduction system

Pathogen Reduction System Prevents Malaria Via Transfusion

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Plasmodium inactivation in whole blood reduces incidence of transfusion-transmitted malaria
A combination drug therapy widely used to treat malaria in adults -- dihydroartemisinin-piperaquine -- also protects pregnant women and their fetuses from the disease

Combo Tx Protects Pregnant Women, Fetuses From Malaria

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Findings suggest older medication is losing effectiveness, researchers say
Among children aged 5 to 17 months

RTS,S Malaria Vaccine More Active Against Matched Infections

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Among children 5 to 17 months, vaccine efficacy higher with matched circumsporozoite protein alleles