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Hydroxychloroquine Level Tied to Thrombosis Risk in Lupus

Rate of thrombotic events lower for patients with mean HCQ blood levels >1,068 versus <648 ng/mL

Could the TB Vaccine Help Prevent COVID-19?

Two-Thirds of Lupus Patients Likely to Take COVID-19 Vaccine

However, national survey uncovered racial differences in uptake, safety concerns

Four distinct physical activity profiles are detectable using activity monitoring among adults with arthritis

Physical Activity, Sleep Profiles Vary in Adults With Arthritis

Balanced activity profile linked to weaker work-related sitting habit, stronger outside walking habit
Some cases of subacute cutaneous lupus erythematosus and systemic lupus erythematosus are drug-induced

Some Lupus Erythematosus Cases Tied to Drug Exposure

Cases found for both cutaneous and systemic lupus, but some previous reports due to protopathic bias
For patients with systemic lupus erythematosus

Risk for COVID-19 Hospitalization Follows Usual Pattern in Lupus

Similar to the general population, predictors of hospitalization include race, comorbidity, and BMI
More than one-third of patients with lupus have experienced significant issues filling their hydroxychloroquine prescription during the COVID-19 pandemic

One-Third of Lupus Patients Have Trouble Refilling Hydroxychloroquine

Patients report lack of availability at usual pharmacy, waiting weeks for refills, only getting partial refills
Adherence to antimalarials may offer a protective effect against type 2 diabetes mellitus among patients with systemic lupus erythematosus

Antimalarials May Cut Risk for Type 2 Diabetes in Lupus Patients

T2DM risk reduced by 39 percent for those with high adherence to antimalarial therapy for managing lupus
Patients with systemic lupus erythematosus have increased colonization with Staphylococcus aureus in cutaneous lupus erythematosus lesions

S. aureus Colonization Increased in Skin Lesions in Lupus Patients

Repression of barrier gene expression, increased S. aureus-binding integrins in SLE keratinocytes found
Peripheral nervous system disease is a component of systemic lupus erythematosus disease activity and has a significant negative impact on health-related quality of life

Peripheral Nervous System Events Not Common in Lupus

History of neuropathy, older age at diagnosis among factors tied to longer time to resolution of PNS events
For patients with systemic lupus erythematosus

Anifrolumab Improves Response at 52 Weeks in Lupus

Rate of composite response showing reduced disease activity higher with anifrolumab versus placebo