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Urate-Lowering Treatments Compared for Gout

More participants receiving low-dose benzbromarone than low-dose febuxostat achieved serum urate target at 12 weeks

From 1990 to 2017

Worldwide Burden of Gout Increased From 1990 to 2017

Men had higher global point prevalence estimates for gout; prevalence higher in older age groups
In an updated American College of Rheumatology guideline

ACR Updates Guideline for Management of Gout

ULT strongly recommended for tophaceous gout, radiographic damage due to gout, gout flares
The antihypertensive medication amlodipine is associated with a lower risk for gout compared with other antihypertensive agents

Amlodipine Better BP Drug for Lower Long-Term Risk for Gout

Compared with chlorthalidone and lisinopril, amlodipine associated with lower risk for gout
Adults with type 2 diabetes newly prescribed a sodium-glucose cotransporter-2 inhibitor have a lower incidence of gout than those prescribed a glucagon-like peptide-1 receptor agonist

Gout Incidence Down With SGLT2 Inhibitors in Type 2 Diabetes

Gout incidence rate significantly reduced with SGLT2 inhibitor versus GLP-1 receptor agonist
Four modifiable risk factors -- body mass index

Four Modifiable Risk Factors Tied to Hyperuricemia

Public health efforts to promote healthy diet and prevent obesity might cut gout cases, authors say
Gout is associated with an elevated risk for chronic kidney disease progression

Gout May Up Risk for Progression of Chronic Kidney Disease

Gout more than doubles the risk for end-stage kidney disease
More than one-fourth of patients with acute gout discharged from the emergency department receive an opioid prescription

Opioids Commonly Prescribed in Emergency Department for Gout

Diabetes, polyarticular gout, prior opioid use tied to increased risk for opioid prescription at discharge
Gout is associated with an increased risk for venous thromboembolism

Gout Linked to Increased Risk for Venous Thromboembolism

Venous thromboembolism risk similar for patients with gout regardless of urate-lowering therapy
The gout medicine Uloric (febuxostat) carries a higher risk of death than allopurinol

FDA: Gout Drug Uloric Increases Risk of Death

Medication is associated with increased risk of heart-related death and death from all causes