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DNA methylation testing may be feasible as a molecular triage of high-risk human papillomavirus-positive individuals for high-resolution anoscopy screening

Progress Made on Genetic Test for Anal Cancer

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But research is still in early stages
Testing for combined urinary PCA3 and TMPRSS2:ERG RNA can improve detection of prostate cancer

Combined Urine Test for T2:ERG, PCA3 Ups Prostate CA Detection

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Combined urinary testing can avoid unnecessary prostate biopsy, while preserving high sensitivity
The addition of selumetinib to docetaxel does not improve progression-free survival among patients with previously treated advanced KRAS-mutant non-small-cell lung cancer

Adding Selumetinib to Docetaxel Doesn’t Up PFS in NSCLC

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No improvement in progression-free survival for previously treated advanced KRAS-mutant NSCLC
A gene mutation appears to speed up the loss of memory and cognitive skills in patients with Alzheimer's disease

BDNF Gene Mutation May Speed Up Memory Loss in Alzheimer’s

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If β-amyloid plaques are present in the brain, process is even faster, researchers say
Eleven novel adiposity variants have been identified after adjustment for physical activity (PA)

Exercise Reduces Weight Gain Effects in Those With FTO Gene

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No evidence for interaction with physical activity for loci other than established FTO locus
Brineura (cerliponase alfa) has been approved by the U.S. Food and Drug Administration to treat a specific form of Batten disease

Enzyme Replacement Drug OK’d for Form of Batten Disease

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Brineura will be used to treat children with late infantile neuronal ceroid lipofuscinosis type 2 Batten
A validated 31-gene expression profile signature improves identification of patients with melanoma at high risk of metastasis when used in combination with the American Joint Committee on Cancer outcome prediction tool

Gene Expression Profile Improves ID of High-Risk Melanoma

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Findings based on use of 31-gene profile along with an online survival prediction tool
A genetic variant that is associated with both multiple sclerosis and systemic lupus erythematosus has been identified

Genetic Variant Tied to MS and Systemic Lupus Identified

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However, BAFF variant was likely selected over time as an adaptive response to malaria
A blood-based genome testing service provides accurate results within 72 hours

Blood-Based Genome Testing Feasible for Rapid Mutation Assay

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Mutation results available within 72 hours for 94 percent of non-small-cell lung CA samples evaluated

T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

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Missense variant in ABCC8 gene also linked to reduced risk of coronary heart disease