Tag: Genetics
Case Highlights Polygenic Risk in Severe Hypertriglyceridemia
Patient with hypertriglyceridemia had polymorphisms producing triglyceride risk score of 19
More Genetic Tests May Benefit Ashkenazi Jewish Cancer Patients
For Ashkenazi Jewish women with breast cancer, mutations identified in other genes, including CHEK2
MYCN Copy Number Tied to Poor Features in Neuroblastoma
Patients with MYCN gain had inferior outcomes, including lowest response rate after chemo
Germline Mutations Up in Men With Prostate CA, One Other CA
However, most of these men do not meet current clinical criteria for germline testing
Whole-Genome Sequencing of Uncertain Clinical Utility
Testing may prompt additional clinical actions of unclear value, researchers say
suPAR Protein Levels Impact CKD Risk With APOL1 Variants
Risk reduced with lower levels of plasma suPAR, strengthened by higher levels
Longer Survival for Midostaurin + Chemotherapy in AML With FLT3
Prolonged overall, event-free survival for patients with acute myeloid leukemia, FLT3 mutation
Family History Questionnaire Ups Genetic Counseling for CRC
Findings in patients who received family history questionnaire before outpatient colonoscopy
Many With Advanced Cancer Want Secondary Germline Findings Info
Attitudes toward learning influenced by patients' personal disease experience, health status
Clonal Hematopoiesis Linked to Coronary Heart Disease
CHIP linked to coronary heart disease, myocardial infarction in humans; atherosclerosis in mice
