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Survivors of Ebola virus disease have localized pathological changes in photoreceptors

Eyes of Ebola Survivors Show Localized Pathological Changes

Retinal lesions mainly non-pigmented, pale gray with perilesional areas of dark without pressure
Two vaccines to prevent Ebola virus disease demonstrated immune responses at one month that were largely maintained through 12 months

Vaccines Elicit Lasting Immune Response Against Ebola

ChAd3-EBO-Z, rVSVΔG-ZEBOV-GP vaccines elicit response that is maintained through 12 months
A small percentage of Ebola virus disease survivors have a novel retinal lesion

Novel Retinal Lesion Seen in Some Ebola Survivors

Novel retinal lesion following anatomical distribution of optic nerve axons seen in 14.6 percent of survivors
After heterologous primary and booster vaccination schedule of the adenovirus type 26 vector vaccine encoding Ebola virus glycoprotein and the modified vaccinia virus Ankara vector vaccine

Immune Responses to Ebola Vaccines Persist at One Year

All active vaccine recipients maintained Ebola virus-specific immunoglobulin responses at day 360
The semen of an Ebola virus disease survivor with preexisting HIV still tested positive for Ebola virus RNA long after recovery from the disease

HIV Coinfection May Play Role in Survival of Ebola RNA in Semen

Case report of EVD survivor with preexisting HIV whose semen was positive 565 days after recovery
A blood test may help determine a patient's chance of surviving Ebola infection

Blood Test May Predict Survival for Patients With Ebola

Findings might lead to more effective patient care, researchers suggest
For healthy adults from Sierra Leon

Recombinant Type-5 Vector-Based Ebola Vaccine Safe

Vaccine is immunogenic in healthy adults from Sierra Leone; optimal dose 8.0 × 1010 viral particles
Ebola virus stays present in semen longer than previously thought

Ebola Virus Lingers in Semen Longer Than Expected

And virus is more likely to be found in male survivors older than 40, researchers report