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Tag: Diabetes: Type I

Completion of full rotavirus vaccination appears to be associated with a reduction in the risk for type 1 diabetes in children

Rotavirus Vaccination Tied to Lower Risk for T1DM in Children

No association seen for partial vaccination and incidence of type 1 diabetes
A 14-day course of an Fc receptor-nonbinding anti-CD3 monoclonal antibody

ADA: Teplizumab Can Delay T1DM Progression in Those at Risk

Median time to type 1 diabetes diagnosis 48.4 months with teplizumab and 24.4 months with placebo
Structured support for patients transitioning from pediatric to adult care for type 1 diabetes may improve outcomes

Transition Support Program May Aid Young Adults With Type 1 Diabetes

However, benefits were not sustained 12 months after completion of the intervention
In patients with type 1 diabetes

Dapagliflozin Improves Glucose Outcomes in Type 1 Diabetes

Benefits observed without increase in time spent in hypoglycemic range
For women with type 1 diabetes

Preterm Birth Linked to Periconception HbA1c in T1DM

Women whose HbA1c levels were consistent with target values also at increased risk for preterm birth
Older adults with type 1 diabetes mellitus spend more than an hour per day in the hypoglycemic range

ENDO: Older T1DM Patients Often Unaware of Hypoglycemic Status

Impaired awareness of hypoglycemia tied to greater amounts of time spent with glucose <70, <54 mg/dL
Standardized reading and mathematics scores do not differ significantly for public schoolchildren with and without type 1 diabetes

Reading, Math Scores No Different for Children With T1DM

Estimated difference in test scores 0.45 after adjustment for variables such as socioeconomic status
Only one in five children and adults with type 1 diabetes in the United States achieve American Diabetes Association goals for glycated hemoglobin

Few Patients With Type 1 Diabetes Meeting HbA1c Goals

Glycemic control not better in 2010 to 2018, despite more use of insulin pumps, continuous monitoring
An improved type 1 diabetes (T1D) genetic risk score (GRS)

Improved Genetic Risk Score Aids Type 1 Diabetes Classification

Revised risk score also improves newborn screening versus HLA genotyping alone
Poor glycemic control is associated with an increased risk for fracture in patients with type 1 diabetes mellitus but not in patients with type 2 diabetes mellitus

Poor Glycemic Control in Type 1 Diabetes Tied to Fracture Risk

Fracture risk up with T2DM and current use of rosiglitazone, pioglitazone regardless of glycemic control