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Tag: Diabetes: Misc.

Among women with gestational diabetes mellitus

Worse Outcomes for GDM With Impaired Insulin Sensitivity

Women with predominant insulin secretion defects have outcomes similar to women with NGT
Skeletal muscle TRIB3 mediates glucose-induced insulin resistance in a mouse model of diabetes

Skeletal Muscle TRIB3 Mediates Diet-Induced Insulin Resistance

TRIB3 overexpressing mice have greater weight gain, worse insulin resistance in response to high-fat diet
About one-third of patients with diabetes mellitus and multivessel coronary artery disease presenting with non-ST-segment elevation myocardial infarction undergo coronary artery bypass graft and more undergo percutaneous coronary intervention

CABG Underused in Diabetes With Multivessel Disease

PCI increasing, but CABG stable for patients presenting with non-ST-segment elevation MI
Infants born to mothers who had gestational diabetes mellitus may be more likely to carry excess fat in early life

Gestational DM Tied to Greater Total Adipose Tissue in Infants

Finding held even with good maternal glycemic control
The prevalence of gestational diabetes mellitus varies across the seasons

Prevalence of Gestational Diabetes Varies Across Seasons

At one- and two-hour diagnostic levels, prevalence is lower in winter and higher in summer
A mother's excess weight gain or elevated blood glucose levels in pregnancy may put her child at increased risk for being overweight or obese

High Maternal Glucose May Adversely ‘Imprint’ Baby

Elevated blood glucose and excess weight during pregnancy may change baby's metabolism
For patients with lipodystrophy

Metreleptin Ups Resting-State Connectivity in Lipodystrophy

Significant increases in hypothalamus; insula, superior temporal gyrus; medial prefrontal cortex
For patients with diabetes

Preadmission SSRI Use Ups Stroke Mortality in Diabetes

Selective serotonin reuptake inhibitor use increases risk for patients hospitalized with stroke
For women with gestational diabetes mellitus

Artemisia Extract Ups Insulin Sensitivity in GDM

Randomized trial shows sizable reduction in fasting plasma glucose, serum insulin levels, HOMA-IR
All-cause and certain cause-specific mortality rates have decreased recently among those with type 1 and 2 diabetes

All-Cause, CVD, DM Mortality Down From 2000 to 2011

Decreases seen in type 1 and 2 diabetes; no change in age-standardized cancer-specific mortality