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Treating systolic blood pressure to a goal of less than 120 mm Hg rather than 140 mm Hg does not result in a significant reduction in the risk for probable dementia

Intensive BP Treatment Does Not Reduce Dementia Risk

But drop seen in risk for MCI and combined rate of cognitive impairment, probable dementia
Algorithms that combine Internet of Things technologies and in-home sensory devices with machine learning techniques can be used to monitor the health and well-being of people with dementia

Machine Learning Methods Can Detect UTI in Dementia Patients

Research team used novel algorithms to ID early symptoms of health declines in dementia patients
Frail kidney transplant recipients have lower cognitive scores than nonfrail recipients four years after transplant

Cognitive Scores After Kidney Transplant Tied to Frailty

Cognitive function first improved then declined 1 to 4 years after transplant in frail recipients
Frailty and Alzheimer disease-related brain changes independently contribute to dementia status

Frailty Could Increase Susceptibility for Dementia

Authors say frailty should be considered in clinical care, management of Alzheimer dementia
In older adults

High Levels of Activity, Motor Ability Linked to Better Cognition

Findings seen in older adults; independent correlations remained for those with Alzheimer disease
Breakdown of the blood-brain barrier may be an early biomarker of cognitive dysfunction

Breakdown of Blood-Brain Barrier May Drive Dementia

Leaky brain capillaries tied to cognitive dysfunction, independent of protein markers for dementia
Patients with hypertension with progression of periventricular white matter hyperintensities have an increased risk for incident mild cognitive impairment

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

Patients with hypertension with progressive cSVD have increased risk for mild cognitive impairment
The number of people living with dementia worldwide more than doubled from 1990 to 2016

Number of People With Dementia Rose Twofold From 1990 to 2016

Overall, 28.8 million disability-adjusted life years due to dementia; 6.4 million attributed to modifiable risks
Both restrictive and obstructive lung disease are associated with an increased risk for incident dementia and mild cognitive impairment

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

Associations seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies
For sedentary adults at risk for cognitive decline

Exercise Promotes Executive Functioning in Sedentary Adults

Significant improvements seen in executive functioning for those at risk for cognitive decline