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Tag: Cancer: Skin

Oxidative stress inhibits metastasis by melanoma cells

Oxidative Stress Inhibits Metastasis by Melanoma Cells

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Metastasizing cells undergo metabolic changes, increasing their ability to withstand oxidative stress
A case of basal cell carcinoma has been described within a port wine stain

Case of Basal Cell Carcinoma Described Within Port Wine Stain

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Tumor described within port wine stain, without previous treatment, including radiotherapy
Nicotinamide appears to reduce non-melanoma skin cancers by 23 percent when taken twice daily

Nicotinamide Could Protect Against Some Skin Cancers

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High-risk patients who took nicotinamide daily developed fewer non-melanoma lesions
Lesion-directed screening has a similar skin cancer detection rate as total-body examination but is substantially less time-consuming

Lesion-Directed Screening Effectively Detects Skin Cancer

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Has similar detection rate as total-body examination, takes much less time
The melanoma patients receptive to an Internet-delivered behavioral intervention to promote skin self-examination and sun protection behaviors may already have higher knowledge of melanoma signs

Internet Interventions Interest Informed Melanoma Patients

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Those most receptive are younger, comfortable with Internet, more knowledgeable about melanoma
Squamous cell carcinoma can develop on long-standing verrucous lesions

Squamous Cell Carcinoma Can Develop on Verrucous Lesions

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Case report describes 64-year-old woman with SCC development on long-standing lesion
New research suggests that surgical removal of melanoma that has metastasized may help patients live more than twice as long as those who receive only medical therapy. The study was scheduled for presentation at the annual meeting of the American College of Surgeons

ACS: Resection Can Up Survival in Metastatic Melanoma

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Those with GI tract metastases had the longest median survival of any patients
The antioxidant N-acetylcysteine appears to accelerate the spread of skin cancer in mice

Safety Concerns Raised for Antioxidant Use in Melanoma

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Mouse study highlights link between N-acetylcysteine and melanoma progression
A new treatment for melanoma that combines two cancer drugs has been approved by the U.S. Food and Drug Administration. The therapy for advanced melanoma includes the drugs Yervoy (ipilimumab) and Opdivo (nivolumab)

FDA Approves New Combo Therapy for Melanoma

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Yervoy and Opdivo previously approved individually to treat melanoma
Patients with cutaneous melanoma metastases have excellent response to intralesional interleukin 2 administered concomitantly with topical imiquimod and a retinoid cream

Intralesional IL-2 Promising for Cutaneous Melanoma Metastases

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Case series demonstrates excellent response with IL-2 combined with topical imiquimod, retinoid cream