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Tag: Cancer: Kidney

Overweight and obesity in adolescence is associated with an increased risk for developing renal cell carcinoma later in life

Extra Weight in Adolescence Tied to Later Risk for Renal Cancer

Among Swedish men, overweight or obesity during adolescence tied to higher risk for renal cell carcinoma
For first-line therapy of metastatic renal cell carcinoma

Combo Regimens Effective for Tx of Metastatic Renal Cell Cancer

Two large trials show benefits for pembrolizumab-axitinib and avelumab-axitinib versus sunitinib
Kidney stones are associated with an increased risk for renal cell carcinoma (RCC)

Kidney Stones Tied to Increased Renal Cell Carcinoma Risk

Risk increased for papillary RCC but not clear-cell RCC; risk for upper tract urothelial carcinoma increased
For patients with renal cell carcinoma

ASTRO: Stereotactic Ablative RT OK for RCC in Solitary Kidneys

Local control, cancer-specific survival at two years similar for patients with solitary, bilateral kidneys
Percutaneous ablation is associated with oncologic outcomes that are similar to those of radical nephrectomy and may be associated with fewer complications than nephron-sparing partial nephrectomy for patients with stage T1a renal cell carcinoma

Study Compares Treatment Options for T1a Renal Cancer

Percutaneous ablation compared with partial, radical nephrectomy for 4,310 patients aged ≥66 years
For patients with metastatic renal cell carcinoma classified as having intermediate or poor prognostic risk

ASCO: Sunitinib Alone Noninferior in Metastatic Renal Cell Cancer

Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival
Type 2 diabetes is independently associated with a greater risk of renal cell carcinoma in women

Type 2 Diabetes Ups Risk of Renal Cancer in Women, but Not Men

Association strongest in patients with diabetes duration of five years or less
For patients with previously untreated clear-cell advanced renal-cell carcinoma

Nivolumab Plus Ipilimumab Tops Sunitinib for Advanced Renal CA

Overall survival, objective response higher than sunitinib for untreated clear-cell advanced RCC
For patients with metastatic renal cell carcinoma

Atezolizumab + Bevacizumab Shows Benefit in Met Renal CA

Progression-free survival benefit for patients with untreated metastatic renal cell carcinoma
From 2003 to 2015 there was an increase in use of robotic-assisted radical nephrectomy

Robotic Radical Nephrectomy Becoming More Common

And robotic laparoscopy for rectal cancer resection does not reduce risk for conversion to open surgery